Efficacy of blood parameters as indicators of the need for overdue urgent cholecystectomy in elderly patients with acute cholecystitis

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dc.contributor.authorKubat, Mehmet
dc.contributor.authorSengul, Serkan
dc.contributor.authorSahin, Serdar
dc.date.accessioned2026-01-24T12:29:13Z
dc.date.available2026-01-24T12:29:13Z
dc.date.issued2023
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractBACKGROUND: Although early cholecystectomy is recommended for patients with acute cholecystitis, conservative treatment followed by delayed cholecystectomy (DC) is a highly preferred modality, especially in older adult patients. However, some severe cases require overdue urgent cholecystectomy (OC). This study aimed to evaluate the ability of laboratory findings and Tokyo severity classification (TokyoSC) to differentiate those with the need for OC among elderly patients.METHODS: Laboratory/radiological/clinical findings of geriatric patients with acute cholecystitis on admission and TokyoSC were retrospectively analyzed. The DC and OC groups were compared. RESULTS: The mean age of the 164 patients was 72.3 +/- 6.4 years. White blood cell, neutrophil (NEU), immature granulocyte (IG), C-reactive protein, neutrophil-to-lymphocyte ratio (NLR), and TokyoSC parameters were all significant at P<0.001 in differentiation. NLR had a specificity of 98%, and TokyoSC had a sensitivity of 98%. CONCLUSION: NLR, NEU, IG, and TokyoSC were effective in differentiating patients who needed OC while planning conservative treatment + DC for older adult patients who were followed up due to acute cholecystitis. If the NLR is >9.9 and TokyoSC is moderate/ high, early cholecystectomy should be preferred instead of conservative treatment + DC in aged patients.
dc.identifier.doi10.14744/tjtes.2023.0000
dc.identifier.endpage1254
dc.identifier.issn1306-696X
dc.identifier.issn1307-7945
dc.identifier.issue11
dc.identifier.pmid37889024
dc.identifier.scopus2-s2.0-85175280821
dc.identifier.scopusqualityQ3
dc.identifier.startpage1248
dc.identifier.trdizinid1264629
dc.identifier.urihttps://doi.org/10.14744/tjtes.2023.0000
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1264629
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5208
dc.identifier.volume29
dc.identifier.wosWOS:001096720400006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Assoc Trauma Emergency Surgery
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260121
dc.subjectAcute cholecystitis
dc.subjectaged
dc.subjectcholecystectomy
dc.subjectc-reactive protein
dc.subjectneutrophil-to-lymphocyte ratio
dc.subjectseverity grading
dc.titleEfficacy of blood parameters as indicators of the need for overdue urgent cholecystectomy in elderly patients with acute cholecystitis
dc.title.alternativeAkut kolesistitli yaşlı hastalarda gecikmiş acil kolesistektomi ihtiyacının göstergesi olarak kan parametrelerinin etkinliği
dc.typeArticle

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