Wound healing effects of methanol extract of Laurocerasus officinalis roem

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dc.contributor.authorAyla, Şule
dc.contributor.authorOkur, Mehmet Evren
dc.contributor.authorGünal, Mehmet Yalçın
dc.contributor.authorÖzdemir, Ekrem Musa
dc.contributor.authorPolat, Derya Çiçek
dc.contributor.authorYoltaş, Ayşegül
dc.contributor.authorBiçeroğlu, Özge
dc.contributor.authorKarahüseyinoğlu, Serçin
dc.date.accessioned2021-02-19T21:16:29Z
dc.date.available2021-02-19T21:16:29Z
dc.date.issued2019
dc.departmentALKÜ
dc.descriptionGunal, Mehmet/0000-0001-7702-2441; okur, mehmet evren/0000-0001-7706-6452; Ayla, Sule/0000-0003-2143-5268; Karahuseyinoglu, Sercin/0000-0001-5531-2587; OZDEMIR, EKREM MUSA/0000-0001-9416-7757
dc.description.abstractLaurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using an excisional wound model model in mice. We used four groups of eight mice as follows: untreated (control), empty gel, extract +gel (L. officinalis +gel), and Madecassol (R) groups. All treatments were applied topically once daily. The scar area, percentage wound closure and epithelization time were measured. L. officinalis promoted wound healing and increased granulation tissue, epidermal regeneration and angiogenesis. L. officinalis extract, which is known for its antioxidant and antimicrobial activities, may be useful for promoting wound healing.
dc.identifier.doi10.1080/10520295.2018.1539242
dc.identifier.endpage188en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue3en_US
dc.identifier.pmid30409033
dc.identifier.scopusqualityQ2
dc.identifier.startpage180en_US
dc.identifier.urihttps://doi.org/10.1080/10520295.2018.1539242
dc.identifier.urihttps://hdl.handle.net/20.500.12868/450
dc.identifier.volume94en_US
dc.identifier.wosWOS:000469009000004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor0-belirlenecek
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofBiotechnic & Histochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntimicrobial
dc.subjectantioxidant
dc.subjectextract
dc.subjectLaurocerasus officinalis
dc.subjectmice
dc.subjectwound healing
dc.titleWound healing effects of methanol extract of Laurocerasus officinalis roem
dc.typeArticle

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