Wound healing effects of methanol extract of Laurocerasus officinalis roem
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Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using an excisional wound model model in mice. We used four groups of eight mice as follows: untreated (control), empty gel, extract +gel (L. officinalis +gel), and Madecassol (R) groups. All treatments were applied topically once daily. The scar area, percentage wound closure and epithelization time were measured. L. officinalis promoted wound healing and increased granulation tissue, epidermal regeneration and angiogenesis. L. officinalis extract, which is known for its antioxidant and antimicrobial activities, may be useful for promoting wound healing.
Açıklama
Gunal, Mehmet/0000-0001-7702-2441; okur, mehmet evren/0000-0001-7706-6452; Ayla, Sule/0000-0003-2143-5268; Karahuseyinoglu, Sercin/0000-0001-5531-2587; OZDEMIR, EKREM MUSA/0000-0001-9416-7757
Anahtar Kelimeler
Antimicrobial, antioxidant, extract, Laurocerasus officinalis, mice, wound healing
Kaynak
Biotechnic & Histochemistry
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
94
Sayı
3
