The effect of intracerebral structure volumes on idiopathic intracranial hypertension

dc.contributor.authorÖzkal, Birol
dc.contributor.authorÖzen, Özkan
dc.date.accessioned2021-02-19T21:16:31Z
dc.date.available2021-02-19T21:16:31Z
dc.date.issued2021
dc.departmentALKÜ
dc.description.abstractBackground This aim of this study was to assess the effect of idiopathic intracranial hypertension (IIH) in the development of intracranial hypertension by measuring patients' cerebrospinal fluid (CSF), brain, and segment volumes. IIH is a disease of unknown cause characterized by chronic CSF pressure elevation and papillary edema. Under the Monro-Kellie doctrine, efforts have been made to explain the disease through an increase in the volumes of one or two of brain, blood or CSF in the intracranial cavity, although these have not been completely successful. Methods Twelve IIH patients diagnosed based on the modified Dandy criteria and 15 age- and sex-compatible healthy controls were included in the study. Cases' 3D T1 sequence images were evaluated using the voxel-based volumetric analysis system (volBrain). Intracranial cavity extraction, macrostructures, and subcortical structure volumes were measured and compared. Results No statistically significant differences were observed between control cases' and IIH patients' CSF, cerebrum, cerebellum, brainstem, and subcortical structure volumes. Conclusion IIH arises from a chronic cause that does not impair the volumetric balance between structures inside the intracerebral cavity.
dc.identifier.doi10.1097/WNR.0000000000001552
dc.identifier.endpage22en_US
dc.identifier.issn0959-4965
dc.identifier.issn1473-558X
dc.identifier.issue1en_US
dc.identifier.pmid33196546
dc.identifier.scopusqualityQ3
dc.identifier.startpage16en_US
dc.identifier.urihttps://doi.org/10.1097/WNR.0000000000001552
dc.identifier.urihttps://hdl.handle.net/20.500.12868/463
dc.identifier.volume32en_US
dc.identifier.wosWOS:000596659800003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor0-belirlenecek
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofNeuroreport
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectbrain volume
dc.subjectcerebrospinal fluid volume
dc.subjectidiopathic intracranial hypertension
dc.subjectprimary pseudotumor cerebri
dc.subjectvoxel-based morphometry
dc.titleThe effect of intracerebral structure volumes on idiopathic intracranial hypertension
dc.typeArticle

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