The effect of intracerebral structure volumes on idiopathic intracranial hypertension
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Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background This aim of this study was to assess the effect of idiopathic intracranial hypertension (IIH) in the development of intracranial hypertension by measuring patients' cerebrospinal fluid (CSF), brain, and segment volumes. IIH is a disease of unknown cause characterized by chronic CSF pressure elevation and papillary edema. Under the Monro-Kellie doctrine, efforts have been made to explain the disease through an increase in the volumes of one or two of brain, blood or CSF in the intracranial cavity, although these have not been completely successful. Methods Twelve IIH patients diagnosed based on the modified Dandy criteria and 15 age- and sex-compatible healthy controls were included in the study. Cases' 3D T1 sequence images were evaluated using the voxel-based volumetric analysis system (volBrain). Intracranial cavity extraction, macrostructures, and subcortical structure volumes were measured and compared. Results No statistically significant differences were observed between control cases' and IIH patients' CSF, cerebrum, cerebellum, brainstem, and subcortical structure volumes. Conclusion IIH arises from a chronic cause that does not impair the volumetric balance between structures inside the intracerebral cavity.
Açıklama
Anahtar Kelimeler
brain volume, cerebrospinal fluid volume, idiopathic intracranial hypertension, primary pseudotumor cerebri, voxel-based morphometry
Kaynak
Neuroreport
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
32
Sayı
1
