The relationship between oral cancer and cadmium: a review

dc.contributor.authorŞatır, Samed
dc.date.accessioned2024-10-24T10:57:11Z
dc.date.available2024-10-24T10:57:11Z
dc.date.issued2022
dc.departmentALKÜ, Fakülteler, Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Radyolojisi Ana Bilim Dalı
dc.description.abstractCadmium (Cd) has been classifed as a type I carcinogen. Since it is ingested orally through food and tobacco use, Cd is likely to be closely related to oral cancers. The relationship between cadmium and oral cancer was investigated using papers on Pubmed and Web of Science. Thus a total of 11 studies from these databases were included in the review. Cd concentrations were signifcantly higher in both the blood and hair of oral cancer patients than in controls. Additionally, it has been reported that Cd increases the activity of reactive oxygen species. Tobacco plants contain varying levels of Cd. The presence of high Cd concentrations in patients who use tobacco products and develop oral cancer is strong evidence that Cd is directly related to oral cancer. While planning a study to determine the Cd concentrations in biological samples, it is advisable to examine the methodologies of previous studies and to avoid technical defciencies. New cell line studies are required to explain the relationship between Cd and autophagy-apoptosis.
dc.identifier.doihttps://doi.org/10.1007/s11033-021-07000-w
dc.identifier.endpage2419en_US
dc.identifier.issue49en_US
dc.identifier.startpage2413en_US
dc.identifier.urihttps://link.springer.com/article/10.1007/s11033-021-07000-w
dc.identifier.urihttps://hdl.handle.net/20.500.12868/2510
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofMolecular Biology Reports
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCadmium
dc.subjectOral cancer
dc.subjectOral squamous cell carcinoma
dc.subjectAutophagy
dc.titleThe relationship between oral cancer and cadmium: a review
dc.typeArticle

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