The Relationship Between Blood Neutrophil to Lymphocyte Ratio and Tumor Size, Tumor Number, Macrovascular Invasion in Patients with Hepatocellular Carcinoma

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dc.contributor.authorCakir, Ozlem Ozer
dc.date.accessioned2026-01-24T12:00:51Z
dc.date.available2026-01-24T12:00:51Z
dc.date.issued2019
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractAim: We aimed to show the relationship between blood neutrophil to lymphocyteratio that is systemic inflammatory marker and tumor s ize, tumor number, macrovascular invasion at the time of diagnosis in patients with hepatocellular carcinoma.Methods: A total 48 patients diagnosed with hepatocellular carcinoma were includedin our study. The patients were divided into two groups according to themedian neutrophil to lymphocyte ratio.Results: A total of 48 patients (11 female, 37 male) were included in our study.The mean age of the patients were 67.18±9.51 years-old. The median neutrophil tolym-phocyte ratio was 3.17. There were significant association between neutrophil tolym-phocyte ratio > 3.17 and macrovascular invasion, the tumor number> 3, thetumor size> 5 cm, Child-Turcot-Pugh score, Model for End-stage Liver DiseaseSodium score, C-reactive protein and blood sodium level (p: 0.005, p: 0.009, p<0.001, p: 0.003, p:0.008, p: 0.035 and p < 0.001, respectively). Multiple logisticlineer regres-sion analysis showed that NLR> 3.17 was an independent predictor oftumor size> 5 cm and hyponatremia in patients with hepatocellular carcinoma (p:0.010, p: 0.012, respectively).Conclusions: The value of blood neutrophil to lymphocyte ratio at the time of diagnosis in patients with hepatocellular carcinoma was a good predictor of tumor sizeand grade of disease.
dc.identifier.doi10.30565/medalanya.551550
dc.identifier.endpage212
dc.identifier.issn2587-0319
dc.identifier.issue3
dc.identifier.startpage207
dc.identifier.trdizinid376675
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/376675
dc.identifier.urihttps://doi.org/10.30565/medalanya.551550
dc.identifier.urihttps://hdl.handle.net/20.500.12868/3773
dc.identifier.volume3
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofActa Medica Alanya
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR-Dizin_20260121
dc.subjectGenel ve Dahili Tıp,Onkoloji
dc.titleThe Relationship Between Blood Neutrophil to Lymphocyte Ratio and Tumor Size, Tumor Number, Macrovascular Invasion in Patients with Hepatocellular Carcinoma
dc.typeArticle

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