The Relationship Between Blood Neutrophil to Lymphocyte Ratio and Tumor Size, Tumor Number, Macrovascular Invasion in Patients with Hepatocellular Carcinoma
Yükleniyor...
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: We aimed to show the relationship between blood neutrophil to lymphocyteratio that is systemic inflammatory marker and tumor s ize, tumor number, macrovascular invasion at the time of diagnosis in patients with hepatocellular carcinoma.Methods: A total 48 patients diagnosed with hepatocellular carcinoma were includedin our study. The patients were divided into two groups according to themedian neutrophil to lymphocyte ratio.Results: A total of 48 patients (11 female, 37 male) were included in our study.The mean age of the patients were 67.18±9.51 years-old. The median neutrophil tolym-phocyte ratio was 3.17. There were significant association between neutrophil tolym-phocyte ratio > 3.17 and macrovascular invasion, the tumor number> 3, thetumor size> 5 cm, Child-Turcot-Pugh score, Model for End-stage Liver DiseaseSodium score, C-reactive protein and blood sodium level (p: 0.005, p: 0.009, p<0.001, p: 0.003, p:0.008, p: 0.035 and p < 0.001, respectively). Multiple logisticlineer regres-sion analysis showed that NLR> 3.17 was an independent predictor oftumor size> 5 cm and hyponatremia in patients with hepatocellular carcinoma (p:0.010, p: 0.012, respectively).Conclusions: The value of blood neutrophil to lymphocyte ratio at the time of diagnosis in patients with hepatocellular carcinoma was a good predictor of tumor sizeand grade of disease.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp,Onkoloji
Kaynak
Acta Medica Alanya
WoS Q Değeri
Scopus Q Değeri
Cilt
3
Sayı
3
