Phytochemical Composition and Biological Activities of Angelica sylvestris L. var. stenoptera Ave-Lall ex Boiss.: An Endangered Medicinal Plant of Northeast Turkey

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dc.authorid0000-0001-5381-2924
dc.authorid0000-0003-0534-3996
dc.contributor.authorKaracelik, Ayca Aktas
dc.contributor.authorTurkucar, Semra Alkan
dc.contributor.authorKarakose, Mustafa
dc.date.accessioned2026-01-24T12:30:49Z
dc.date.available2026-01-24T12:30:49Z
dc.date.issued2022
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractAngelica sylvestris L. var. stenoptera Ave-Lall ex Boiss. (ASS) is an endangered endemic plant to Turkey. The objective of the study was to determine antioxidant activities, total phenolics, and phytochemical properties of methanolic extracts (MEs) and essential oil (EO) from ASS for the first time with the methods of 2,2-diphenyl-1-picrylhydrazyl (DPPH center dot) radical scavenging activities, 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS(center dot+)), ferric reducing/antioxidant power (FRAP), the Folin-Ciocalteu, liquid chromatography-tandem mass spectrometry (LC-MS/MS), and gas chromatography-mass spectrometry (GC-MS), respectively. The leaf extract of ASS was found to be the richest in phenolic content (543.91 +/- 6.33 GAE, mu g/mL) and showed the highest DPPH center dot and FRAP activities (IC50: 0.1140 +/- 0.0011 mg/mL, 675.62 +/- 15.01 mu M TEAC). EO of ASS root showed DPPH center dot and FRAP activities (IC50: 1.3248 +/- 0.0572 mg/mL, 346.67 +/- 12.75 mu M TEAC). 19 phenolics were detected in MEs of different parts of ASS by LC/MS/MS. In the chemical composition of ASS root EO by GC/MS, globulol (70.70%) was found to be the major compound. Our results indicate that ASS can be used a source of phytochemicals and antioxidants for conservation and sustainability of endangered plants.
dc.description.sponsorshipGiresun University Espiye Vocational School Funding Source: Medline
dc.identifier.doi10.1002/cbdv.202200552
dc.identifier.issn1612-1872
dc.identifier.issn1612-1880
dc.identifier.issue10
dc.identifier.pmid36085404
dc.identifier.scopus2-s2.0-85138960805
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1002/cbdv.202200552
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5445
dc.identifier.volume19
dc.identifier.wosWOS:000861445000001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley-V C H Verlag Gmbh
dc.relation.ispartofChemistry & Biodiversity
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260121
dc.subjectAngelica sylvestris
dc.subjectantioxidant activity
dc.subjectLC-MS/MS
dc.subjectGC-MS
dc.subjectessential oil
dc.titlePhytochemical Composition and Biological Activities of Angelica sylvestris L. var. stenoptera Ave-Lall ex Boiss.: An Endangered Medicinal Plant of Northeast Turkey
dc.typeArticle

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