Impact of malnutrition on pupillary responses in pediatric population

Basit Öğe Kaydı
dc.authorid0000-0002-0708-5508
dc.contributor.authorKocabas, Dilara Ozkoyuncu
dc.contributor.authorYavrum, Fuat
dc.contributor.authorSukun, Elmas Yuksel
dc.contributor.authorYavrum, Begum
dc.date.accessioned2026-01-24T12:29:09Z
dc.date.available2026-01-24T12:29:09Z
dc.date.issued2026
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractPurpose : To investigate the effect of nutritional status on pupillary responses in children aged 5 to 18 years. Methods : This cross-sectional study comprised 92 eyes of malnourished children and 80 eyes of age- and gender-matched healthy children based on BMI Z-score. Serum ferritin, hemoglobin, serum 25-hydroxyvitamin D, and vitamin B12 levels were recorded. Pupillary responses were taken using Sirius topography (CSO, Italy) with the automated pupillometry function. Static pupillometry consisted of pupil diameters at scotopic, mesopic, and photopic luminances. In dynamic pupillometry, the mean pupil dilation speed at the 10th second was calculated by dividing the distance by time in each 0.2 s period. Results : No significant difference was observed between the groups regarding age, gender, visual acuity, and spherical equivalent (p > 0.05). Mean hemoglobin, serum ferritin, serum 25-hydroxyvitamin D, and vitamin B12 levels were lower in malnourished children than healthy children (p < 0.001). The malnutrition group had lower mean pupil diameters under all luminance and higher speed of pupil dilation compared to the control group (p < 0.05). While malnutrition subgroups were similar in terms of pupil diameters under all luminance (p > 0.05), the speed of pupil dilation was significantly different between the groups (p = 0.024). BMI z-score was positively correlated with mesopic and photopic pupil diameter but also negatively correlated with the speed of pupil dilation (p < 0.05). Conclusion : Malnourished children have smaller pupil diameters and higher speed of pupil dilation than healthy controls, indicating an autonomic impairment.
dc.identifier.doi10.1177/11206721251367568
dc.identifier.endpage74
dc.identifier.issn1120-6721
dc.identifier.issn1724-6016
dc.identifier.issue1
dc.identifier.pmid40820357
dc.identifier.scopus2-s2.0-105013874704
dc.identifier.scopusqualityQ2
dc.identifier.startpage67
dc.identifier.urihttps://doi.org/10.1177/11206721251367568
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5137
dc.identifier.volume36
dc.identifier.wosWOS:001552745300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Ltd
dc.relation.ispartofEuropean Journal of Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectChildhood
dc.subjectdynamic pupillometry
dc.subjectmalnutrition
dc.subjectstatic pupillometry
dc.titleImpact of malnutrition on pupillary responses in pediatric population
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu