Meibomian gland changes and influencing factors following cataract surgery

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dc.contributor.authorYavrum, Fuat
dc.contributor.authorAlcikaya, Berra
dc.contributor.authorAcar, Aysegul
dc.contributor.authorSahinoglu-Keskek, Nedime
dc.date.accessioned2026-01-24T12:30:58Z
dc.date.available2026-01-24T12:30:58Z
dc.date.issued2025
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractPurpose Meibomian gland dysfunction (MGD) is a leading cause of evaporative dry eye disease (DED), and its exacerbation after cataract surgery has been reported. This study aims to evaluate meibomian gland (MG) morphological and functional changes following cataract surgery and identify influencing factors. Methods This prospective, observational study included 132 patients who underwent phacoemulsification with intraocular lens implantation. Meibomian gland loss (MGL) and non-invasive tear break-up time (NI-BUT) were assessed preoperatively at postoperative week one, and at month one using a corneal topography device via infrared meibography (Sirius, CSO, Italy). Correlations between MGL, NI-BUT, cataract grade, and surgery duration were analyzed. Results Postoperatively, MGL increased at week one (32.0% +/- 15.1) and month one (30.9% +/- 14.5) compared to preoperative values (15.1% +/- 7.0). NI-BUT decreased at both time points (week one: 6.8 s +/- 4.3; month one: 6.7 s +/- 4.6; preoperative: 9.4 s +/- 4.5). A significant correlation was found between increased MGL and longer surgery duration (p < 0.001). ROC analysis identified a surgical duration threshold of 11.5 min, beyond which MGL changes were more pronounced. Conclusions Cataract surgery induces significant MG changes, with increased MGL and reduced NI-BUT postoperatively. Longer surgical duration is a key risk factor for MG deterioration. These findings highlight the importance of ocular surface management in cataract surgery to improve postoperative outcomes.
dc.identifier.doi10.1007/s10792-025-03872-0
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue1
dc.identifier.pmid41247629
dc.identifier.scopus2-s2.0-105022014265
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1007/s10792-025-03872-0
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5542
dc.identifier.volume45
dc.identifier.wosWOS:001617251800008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofInternational Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260121
dc.subjectCataract surgery
dc.subjectMeibomian glands
dc.subjectOcular surface
dc.subjectTear break up time
dc.titleMeibomian gland changes and influencing factors following cataract surgery
dc.typeArticle

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