The association between knee osteoarthritis and polycystic ovary syndrome in postmenopausal women: preliminary results

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dc.authorid0000-0003-1421-9962
dc.contributor.authorDeniz, A.
dc.contributor.authorKehribar, L.
dc.date.accessioned2026-01-24T12:29:23Z
dc.date.available2026-01-24T12:29:23Z
dc.date.issued2021
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractOBJECTIVE: The comorbidity of many risk factors associated with the etiology of osteoarthritis (OA) and polycystic ovary syndrome (PCOS) is commonly observed. However, to the best of our knowledge, there are no studies in literature on the relationship between PCOS history and knee OA development in postmenopausal women. PATIENTS AND METHODS: A total of 120 postmenopausal women diagnosed with knee osteoarthritis who underwent surgical treatment in our orthopedic clinic and, 80 postmenopausal women who referred to our orthopedic clinic but did not have knee osteoarthritis were randomly included in our study. Body Mass Index (BMI) values, PCOS history and demographic data of the patients in both groups were examined. RESULTS: PCOS was found to be an independent risk factor for OA. PCOS was 2.734 times effective in the development of knee OA, Odd ratio (95% confidence interval) = 2.734 (1.206-6.198) and p-value 0.016. BMI was found to be an independent risk factor for OA. BMI between 25-30 was found to be 2.783 times more effective on knee OA development when compared with BMI<25, Odd Ratio (95% confidence interval) = 2.783 (1.324-5.852) and p-value 0.07. In addition, BMI>30 was found to be 9.237 times more effective on knee OA development when compared with BMI< 25, Odd Ratio (95% confidence interval) = 9.237 (3.992-21.374) and p-value < 0.001. CONCLUSIONS: The history of PCOS was found to be statistically significantly higher in the knee OA group. BMI and PCOS were found to be independent risk factors in the development of knee OA.
dc.identifier.doi10.26355/eurrev_202108_26446
dc.identifier.endpage4899
dc.identifier.issn1128-3602
dc.identifier.issue15
dc.identifier.pmid34355361
dc.identifier.scopus2-s2.0-85111770052
dc.identifier.scopusqualityQ1
dc.identifier.startpage4895
dc.identifier.urihttps://doi.org/10.26355/eurrev_202108_26446
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5326
dc.identifier.volume25
dc.identifier.wosWOS:000681052300005
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260121
dc.subjectKnee osteoarthritis
dc.subjectPolycystic ovary syndrome
dc.subjectBMI
dc.subjectPostmenopause
dc.titleThe association between knee osteoarthritis and polycystic ovary syndrome in postmenopausal women: preliminary results
dc.typeArticle

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