Effectiveness of vedolizumab treatment in two different anti-tumor necrosis factor alpha refractory pouchitis: A case report

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dc.contributor.authorÇakır, Özlem Özer
dc.date.accessioned2021-02-19T21:16:53Z
dc.date.available2021-02-19T21:16:53Z
dc.date.issued2019
dc.departmentALKÜ
dc.description.abstractBACKGROUND Refractory pouchitis is a common cause of pouch failure, which may require surgical excision of the pouch or permanent diversion. We aimed to show the effect of vedolizumab on treatment of the patient with refractory pouchitis. CASE SUMMARY A 32-year-old male with pancolonic ulcerative colitis since the age of 25 with primary failure of infliximab and mesalamine and intolerance of azathioprine, underwent a total proctocolectomy with ileal pouch-anal anastomosis in 2012. He developed chronic diarrhea in 2014, which was watery, 30 per day and accompanied with blood and mucus affecting his quality of life. CONCLUSION Vedolizumab is safe and effective in the management of anti-tumor necrosis factor alpha refractory pouchitis.
dc.identifier.doi10.12998/wjcc.v7.i16.2316
dc.identifier.endpage2321en_US
dc.identifier.issn2307-8960
dc.identifier.issue16en_US
dc.identifier.pmid31531325
dc.identifier.startpage2316en_US
dc.identifier.urihttps://doi.org/10.12998/wjcc.v7.i16.2316
dc.identifier.urihttps://hdl.handle.net/20.500.12868/580
dc.identifier.volume7en_US
dc.identifier.wosWOS:000483364100017
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorÇakır, Özlem Özer
dc.language.isoen
dc.publisherBaishideng Publishing Group Inc
dc.relation.ispartofWorld Journal of Clinical Cases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnti-tumor necrosis factor alpha
dc.subjectRefractory pouchitis
dc.subjectVedolizumab
dc.subjectUlcerative colitis
dc.titleEffectiveness of vedolizumab treatment in two different anti-tumor necrosis factor alpha refractory pouchitis: A case report
dc.typeArticle

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