Evaluation of the antibacterial effects of single and combined use of different irrigation solutions against intracanal enterococcus faecalis

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dc.contributor.authorÖzkan, Hatice Büyüközer
dc.contributor.authorÇobankara, Funda Kont
dc.contributor.authorSayın, Zafer
dc.contributor.authorÖzer, Füsun
dc.date.accessioned2021-02-19T21:16:14Z
dc.date.available2021-02-19T21:16:14Z
dc.date.issued2020
dc.departmentALKÜ
dc.descriptionOzkan, Hatice Buyukozer/0000-0003-4419-1518;
dc.description.abstractObjectives: This study assessed the antibacterial activity of both separate and combined uses of 5.25% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), 17% ethylenediaminetetraacetic acid (EDTA), 3% hydrogen peroxide (H2O2), MTAD, SmearClear (SC) and 13.8% chlorine dioxide (ClO2) irrigation solutions against Enterococcus faecalis. Material and Methods: Two hundred eighty single rooted human premolars were randomly grouped into 26 test and 2 control (negative and positive) groups and were incubated for 24 h with E. faecalis, except for the negative control group. The tested solutions were as follow: NaOCl; CHX; ClO2; MTAD; SC; EDTA; H2O2; NaOCl + CHX; NaOCl + MTAD; SC + NaOCl; EDTA + NaOCl; H2O2 + NaOCl; ClO2 + CHX; CHX + MTAD; SC + CHX; EDTA + CHX; CHX + H2O2; ClO2 + MTAD; SC + ClO2; EDTA + ClO2; ClO2 + H2O2; SC+MTAD; EDTA+MTAD; MTAD + H2O2; SC + H2O2; and EDTA + H2O2. Optic density values were recorded at 0, 6, 12, 18, 24, 30, 36, 42 and 48 h and bacterial growth curve created for each solution. Results: The CHX, MTAD and ClO2 showed a high potential for the elimination of E. faecalis, both alone and in all combinations. The EDTA, H2O2, H2O2+ EDTA, H2O2 + NaOCl and SC + NaOCl groups showed less antibacterial activity than the other groups. The SC + CHX group showed the best antibacterial effect against E. faecalis. Conclusion: The SC + CHX combination can be recommended as the most effective irrigation regimen against E. faecalis in persistent endodontic infections.
dc.description.sponsorshipSelcuk University, Scientific Research Projects Coordination UnitSelcuk University [8102006]
dc.description.sponsorshipThe work was supported by Selcuk University, Scientific Research Projects Coordination Unit with number 8102006 from Konya/Turkey.
dc.identifier.doi10.15644/asc54/3/3
dc.identifier.endpage262en_US
dc.identifier.issn0001-7019
dc.identifier.issn1846-0410
dc.identifier.issue3en_US
dc.identifier.pmid33132388
dc.identifier.scopusqualityQ2
dc.identifier.startpage250en_US
dc.identifier.urihttps://doi.org/10.15644/asc54/3/3
dc.identifier.urihttps://hdl.handle.net/20.500.12868/327
dc.identifier.volume54en_US
dc.identifier.wosWOS:000575915100003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor0-belirlenecek
dc.language.isoen
dc.publisherUniv Zagreb, Sch Dental Medicine
dc.relation.ispartofActa Stomatologica Croatica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectRoot Canal Irrigants
dc.subjectLocal Anti-Infective Agents
dc.subjectE. faecalis
dc.titleEvaluation of the antibacterial effects of single and combined use of different irrigation solutions against intracanal enterococcus faecalis
dc.typeArticle

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