Sexual dysfunction in female subjects with beta-thalassemia minor

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dc.contributor.authorKeşkek, Şakir Özgür
dc.contributor.authorDemirtaş, Derya
dc.contributor.authorUysal, Gülsüm
dc.contributor.authorBaşaran, Enes
dc.date.accessioned2021-02-19T21:20:45Z
dc.date.available2021-02-19T21:20:45Z
dc.date.issued2020
dc.departmentALKÜ
dc.description.abstractBeta thalassemia minor (BTM) is a hereditary disease caused by defective globin synthesis and it is frequently asymptomatic or only mildly anemic. Female sexual dysfunction affects 21–41% of women worldwide. In this study we aimed to investigate female sexual dysfunction in subjects with BTM. A total of 183 subjects who had regular sexual intercourse with marital partners were enrolled in this cross-sectional study. The study group was comprised of 87 subjects with BTM and the control group included 96 healthy subjects. Hemoglobin electrophoresis were performed in all subjects, and all participants were assessed by the Female Sexual Function Index (FSFI) questionnaire and the Arizona Sexual Experience Scale (ASEX). The FSFI scores of the study group were significantly lower than in the control group (19.1 ± 9.6 vs. 25.2 ± 6.6, p < 0.001). Conversely, the ASEX scores of the study group were higher than in the control group (15.2 ± 41 vs. 13.5 ± 6.1, p = 0.0085). Sexual functions were poor in subjects with BTM in this study and we conclude that certain metabolic diseases associated with BTM, such as insulin resistance, hyperglycemia and dyslipidemia, may be the main causes of sexual dysfunctions in these subjects. © 2020, The Author(s), under exclusive licence to Springer Nature Limited.
dc.identifier.doi10.1038/s41443-020-0283-z
dc.identifier.endpage362en_US
dc.identifier.issn0955-9930
dc.identifier.issue3en_US
dc.identifier.pmid32341453
dc.identifier.scopusqualityQ1
dc.identifier.startpage358en_US
dc.identifier.urihttps://doi.org/10.1038/s41443-020-0283-z
dc.identifier.urihttps://hdl.handle.net/20.500.12868/649
dc.identifier.volume32en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor0-belirlenecek
dc.language.isoen
dc.publisherSpringer Nature
dc.relation.ispartofInternational Journal of Impotence Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titleSexual dysfunction in female subjects with beta-thalassemia minor
dc.typeArticle

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