Morphometric evaluation of cerebellar lobules in individuals with unilateral vertebral artery hypoplasia

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dc.authorid0000-0002-3805-4245
dc.contributor.authorOzen, Ozkan
dc.contributor.authorYuksel, Yavuz
dc.contributor.authorTorun, Ebru
dc.contributor.authorErgun, Tarkan
dc.date.accessioned2026-01-24T12:30:52Z
dc.date.available2026-01-24T12:30:52Z
dc.date.issued2023
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractPurpose Vertebral arteries (VAs) provide blood circulation to the posterior fossa in general and are the main blood supply of the posterior fossa structures of the brain. Our aim in this study is to analyze the segmental volumetric values of cerebellar structures with the voxel-based volumetric analysis system in individuals with unilateral vertebral artery hypoplasia. Methods In this retrospective study, segmental volumetric values/percentile ratios of cerebellar lobules were calculated using 3D fast spoiled gradient recall acquisition in steady-state (3D T1 FSPGR) MRI sequence images of the brain in individuals with unilateral vertebral artery hypoplasia (VAH) and in those without bilateral VAH and any symptoms of vertebrobasilar insufficiency as the control group was evaluated in volBrain. Results The VAH group consisted of 50 (19 males/31 females) and the control group had 50 (21 males/29 females) individuals. The cerebellar lobule III, IV, VIIIA and X total volumes and the cerebellar lobule I-II, III, IV, VIIIA and X gray matter volumes were lower in the hypoplastic side than the non-hypoplastic cases and also than the contralateral side of the hypoplastic cases in the VAH group. In addition, it was found that that lobules IV and V had lower cortical thickness and lobules I-II had a higher coverage rate in the intracranial cavity in the hypoplastic side than the non-hypoplastic cases and also than the contralateral side of the hypoplastic cases (p < 0.05). Conclusion In this study, it was found that cerebellar lobule III, IV, VIIIA, X total volumes and cerebellar lobule I-II, III, IV, VIIIA, X gray matter volumes in addition to lobule IV, V cortical thicknesses were low in individuals with unilateral VAH. Being aware of these variations and taking them into account during future volumetric studies on the cerebellum are very important.
dc.identifier.doi10.1007/s00276-023-03108-9
dc.identifier.endpage407
dc.identifier.issn0930-1038
dc.identifier.issn1279-8517
dc.identifier.issue4
dc.identifier.pmid36813912
dc.identifier.scopus2-s2.0-85148498591
dc.identifier.scopusqualityQ2
dc.identifier.startpage401
dc.identifier.urihttps://doi.org/10.1007/s00276-023-03108-9
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5504
dc.identifier.volume45
dc.identifier.wosWOS:000937058700003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer France
dc.relation.ispartofSurgical and Radiologic Anatomy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260121
dc.subjectCerebellum
dc.subjectCerebellum segmentation
dc.subjectHypoplasia
dc.subjectMagnetic resonance imaging
dc.subjectVertebral artery
dc.titleMorphometric evaluation of cerebellar lobules in individuals with unilateral vertebral artery hypoplasia
dc.typeArticle

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