Athletic performance, sports experience, and exercise addiction: an association study on ANKK1 gene polymorphism rs1800497

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dc.authorid0000-0003-1001-5348
dc.authorid0000-0003-4026-9883
dc.authorid0000-0001-7861-8204
dc.authorid0000-0002-3029-2310
dc.authorid0000-0002-5488-3158
dc.contributor.authorBayraktar, Isik
dc.contributor.authorCepicka, Ladislav
dc.contributor.authorBarasinska, Magdalena
dc.contributor.authorKazan, Hasan Huseyin
dc.contributor.authorZorba, Erdal
dc.contributor.authorErgun, Mehmet Ali
dc.contributor.authorEken, Ozgur
dc.date.accessioned2026-01-24T12:29:28Z
dc.date.available2026-01-24T12:29:28Z
dc.date.issued2023
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractIntroduction: Exercise addiction is a phenomenon being able to affecting the athletic performance. The gene, ANKK1 and the polymorphism NM_178510.2:c.2137G > A (rs1800497) has been linked to the exercise addiction. However, further studies on diverse populations and sport branches are needed to totally explore the possible association of this polymorphism with the athletic performance. Thus, the present study aims to decipher any possible relations of the rs1800497 polymorphism with the athletic performance/personal best (PB) and sport experience of elite athletes. Methods: Sixty volunteer elite athletes (31 sprint/power and 29 endurance) and 20 control/sedentary participated in the study. The polymorphism was genotyped using whole exome sequencing approach and PB were determined according to the International Association of Athletics Federations (IAAF) score. Results: Our results underlined that there were not any significance differences for both allele and genotype frequencies between the groups in terms of athletic performance, although the frequency of allele G was higher (p > 0.05). Nevertheless, sport experience significantly associated with the rs1800496 polymorphism (p < 0.05). Discussion: In conclusion, genotype G/G could be inferred to be linked to the higher sport experience and athletic performance. Still, further studies with higher number of participants are needed to conclude the association of this polymorphism with athletic parameters.
dc.description.sponsorshipGazi University Rectorate (Scientific Research Projects Coordination's Unit) [TCD-2021-7116]; European Union [CZ.02.2.69/0.0/0.0/18_054/0014627]
dc.description.sponsorship& nbsp;The study was supported by Gazi University Rectorate (Scientific Research Projects Coordination's Unit, Project number: TCD-2021-7116). Published with the financial support of the European Union, as part of the project entitled Development of capacities and environment for boosting the international, intersectoral, and interdisciplinary cooperation at UWB, project reg. no. CZ.02.2.69/0.0/0.0/18_054/0014627.
dc.identifier.doi10.3389/fpsyg.2023.1182575
dc.identifier.issn1664-1078
dc.identifier.pmid37588243
dc.identifier.scopus2-s2.0-85168296586
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3389/fpsyg.2023.1182575
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5386
dc.identifier.volume14
dc.identifier.wosWOS:001047878500001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherFrontiers Media Sa
dc.relation.ispartofFrontiers in Psychology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectANKK1
dc.subjectathletics
dc.subjectathletic performance
dc.subjectexercise addiction
dc.subjectsport experience
dc.subjectrs1800497 polymorphism
dc.titleAthletic performance, sports experience, and exercise addiction: an association study on ANKK1 gene polymorphism rs1800497
dc.typeArticle

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