Iron oxide/poly(3,4-ethylenedioxythiophene): poly(styrene sulfonate) glassy carbon electrode as a novel label-free electrochemical microRNA-21 sensor

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dc.contributor.authorDulgerbaki, Cigdem
dc.contributor.authorOksuz, Aysegul Uygun
dc.date.accessioned2026-01-24T12:31:27Z
dc.date.available2026-01-24T12:31:27Z
dc.date.issued2024
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractMicroRNAs (miRNAs), a type of non-protein-coding and small RNAs, are encouraging molecular biomarkers for prior diagnosis of the certain diseases. Here, an electrochemical sensor based on iron oxide/poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate (Fe3O4/PEDOT:PSS) hybrid coated glassy carbon electrode (GCE) is reported to determine microRNA-21 (miRNA-21) as a biosensing platform based on hybridization event. The biosensor was characterized by cyclic voltammetry (CV) measurements. The Fe3O4/PEDOT:PSS demonstrated good sensing performance, including a wide detection range (0.1 pM-1 mu M) and a low detection limit (0.023 pM) for potential medical applications.
dc.identifier.doi10.1080/10739149.2023.2221339
dc.identifier.endpage79
dc.identifier.issn1073-9149
dc.identifier.issn1525-6030
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85161909606
dc.identifier.scopusqualityQ2
dc.identifier.startpage67
dc.identifier.urihttps://doi.org/10.1080/10739149.2023.2221339
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5889
dc.identifier.volume52
dc.identifier.wosWOS:001007670700001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofInstrumentation Science & Technology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260121
dc.subjectIron oxide
dc.subjectpoly(3
dc.subject4-ethylenedioxythiophene)
dc.subjectpoly(styrene sulfonate) (PEDOT
dc.subjectPSS)
dc.subjectglassy carbon electrode (GCE)
dc.subjectcyclic voltammetry (CV)
dc.subjectmicroRNA-21 (miRNA-21)
dc.subjectelectrochemical biosensor
dc.titleIron oxide/poly(3,4-ethylenedioxythiophene): poly(styrene sulfonate) glassy carbon electrode as a novel label-free electrochemical microRNA-21 sensor
dc.typeArticle

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