Iron oxide/poly(3,4-ethylenedioxythiophene): poly(styrene sulfonate) glassy carbon electrode as a novel label-free electrochemical microRNA-21 sensor
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Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
MicroRNAs (miRNAs), a type of non-protein-coding and small RNAs, are encouraging molecular biomarkers for prior diagnosis of the certain diseases. Here, an electrochemical sensor based on iron oxide/poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate (Fe3O4/PEDOT:PSS) hybrid coated glassy carbon electrode (GCE) is reported to determine microRNA-21 (miRNA-21) as a biosensing platform based on hybridization event. The biosensor was characterized by cyclic voltammetry (CV) measurements. The Fe3O4/PEDOT:PSS demonstrated good sensing performance, including a wide detection range (0.1 pM-1 mu M) and a low detection limit (0.023 pM) for potential medical applications.
Açıklama
Anahtar Kelimeler
Iron oxide, poly(3, 4-ethylenedioxythiophene), poly(styrene sulfonate) (PEDOT, PSS), glassy carbon electrode (GCE), cyclic voltammetry (CV), microRNA-21 (miRNA-21), electrochemical biosensor
Kaynak
Instrumentation Science & Technology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
52
Sayı
1
