The role of blood nitric oxide level in predicting return of spontaneous circulation: a prospective case-control study

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dc.authorid0000-0002-1685-5332
dc.authorid0000-0003-3053-1956
dc.contributor.authorBayramoglu, Atif
dc.contributor.authorTekin, Erdal
dc.contributor.authorKurt, Engin
dc.contributor.authorKasali, Kamber
dc.contributor.authorKurt, Nezahat
dc.date.accessioned2026-01-24T12:29:17Z
dc.date.available2026-01-24T12:29:17Z
dc.date.issued2024
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractOBJECTIVE: The aim of this study was to investigate whether there is a difference in serum nitric oxide levels between patients who return spontaneously after cardiopulmonary resuscitation and those who do not. We also examined the potential of using serum nitric oxide levels as a marker to make an accurate decision about patient survival. METHODS: We included 100 consecutive patients who were brought to the emergency clinic due to cardiac arrest. Blood samples were taken from these patients at admission, 30 min after admission, and when resuscitation was terminated. RESULTS: We found that there was a significant difference in NO1 and NO3 values between the group of patients who did not return after cardiopulmonary resuscitation and the group in which spontaneous circulation returned. The NO1 value was significant in the receiver operating characteristic (ROC) analysis, while the NO3 value was not. A higher NO1 value provided a higher rate of survival. CONCLUSION: Our findings suggest that nitric oxide may be a useful parameter to support the decision about patient survival. A higher NO1 value is associated with a better prognosis and survival rate. Therefore, serum nitric oxide levels may be a suitable indicator to support the decision-making process regarding patient survival.
dc.description.sponsorshipTUBITAK through the ARDEB 1002 Rapid Support Program [219S396]
dc.description.sponsorshipthis article is derived from a project supported by TUBITAK through the ARDEB 1002 Rapid Support Program (No. 219S396).
dc.identifier.doi10.1590/1806-9282.20240155
dc.identifier.issn0104-4230
dc.identifier.issn1806-9282
dc.identifier.issue8
dc.identifier.pmid39230143
dc.identifier.scopus2-s2.0-85203210910
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1590/1806-9282.20240155
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5239
dc.identifier.volume70
dc.identifier.wosWOS:001306215800001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAssoc Medica Brasileira
dc.relation.ispartofRevista Da Associacao Medica Brasileira
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectCardiopulmonary resuscitation
dc.subjectNitric oxide
dc.subjectRosc
dc.titleThe role of blood nitric oxide level in predicting return of spontaneous circulation: a prospective case-control study
dc.typeArticle

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