P-wave dispersion in patients with premature ejaculation

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dc.authorid0000-0002-4325-1075
dc.contributor.authorAkkoc, Ali
dc.contributor.authorOncel, Can Ramazan
dc.contributor.authorCemal, Koseoglu
dc.date.accessioned2026-01-24T12:26:38Z
dc.date.available2026-01-24T12:26:38Z
dc.date.issued2025
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractBackground: Premature ejaculation (PE) is one of the common male sexual disorders and is associated with autonomic nervous system imbalance. P-wave dispersion (PWD), a marker of atrial electrical heterogeneity and a predictor of atrial arrhythmias, has not been previously investigated in the PE population. This study aimed to investigate PWD in patients with PE and to evaluate whether the subtypes of PE, namely acquired (APE) and lifelong (LLPE), differ in terms of atrial conduction parameters. Methods: Seventy-eight male patients were included in the study. The distribution of patients was 40 healthy controls, 21 patients with APE, and 17 patients with LLPE. All patients underwent 12-lead electrocardiography to evaluate PWD. Echocardiographic, hormonal, and biochemical parameters were recorded to exclude confounding factors. PWD was defined as the difference between the maximum (Pmax) and minimum P wave durations (Pmin). Results: PWD was significantly increased in both PE groups compared to the control group (APE: 44.4 +/- 4.1 ms; LLPE: 48.1 +/- 2.1 ms; control: 38.2 +/- 3.4 ms; p < 0.001). Pmin was significantly lower in the PE groups, while Pmax remained comparable among all groups. There was no significant difference in PWD between the PE groups (p = 0.38). All patients had normal echocardiographic and hormonal parameters, and there were no significant differences in age, body mass index, blood pressure, or heart rate between the groups. Conclusions: PWD was significantly higher in patients with PE. This indicates that the patients of PE are at a higher risk of developing cardiovascular diseases like atrial fibrillation.
dc.identifier.doi10.4081/aiua.2025.14073
dc.identifier.issn1124-3562
dc.identifier.issn2282-4197
dc.identifier.issue3
dc.identifier.pmid40824062
dc.identifier.scopus2-s2.0-105017678467
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.4081/aiua.2025.14073
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4829
dc.identifier.volume97
dc.identifier.wosWOS:001589468200028
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPagepress Publ
dc.relation.ispartofArchivio Italiano Di Urologia E Andrologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectPremature ejaculation
dc.subjectP-wave dispersion
dc.subjectAtrial fibrillation
dc.subjectCardiovascular disease
dc.subjectElectrocardiography
dc.titleP-wave dispersion in patients with premature ejaculation
dc.typeArticle

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