Determining the sweet detection threshold of COVID-19 patients during infection and recovery periods

Basit Öğe Kaydı
dc.authorid0000-0003-0224-1919
dc.authorid0000-0003-1341-1987
dc.authorid0000-0003-2723-0255
dc.authorid0000-0001-8417-868X
dc.contributor.authorAlsanei, Woroud
dc.contributor.authorAlhussin, Esraa
dc.contributor.authorNatto, Zuhair S.
dc.contributor.authorAfeef, Marwah
dc.contributor.authorAktar, Tugba
dc.date.accessioned2026-01-24T12:29:11Z
dc.date.available2026-01-24T12:29:11Z
dc.date.issued2024
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractBackground The loss of taste and smell is a common symptom of COVID-19, affecting individuals' quality of life and nutritional status. Detecting sweet thresholds during infection and recovery periods can assist in implementing dietary modifications and nutritional strategies for these patients.Objective To investigate the changes and differences in sweet detection thresholds of confirmed COVID-19 patients on Day 1, Day 10, and Day 14 of the infection and recovery periods.Methods The demographic factors such as gender, smoking status, BMI, and age group were abstracted on Excel sheet from the medical health records for confirmed COVID-19 patients, who were admitted to King Fahad General Hospital in Jeddah, Saudi Arabia, a COVID-19 care facility, from September 2021 to July 2022. Sweet detection thresholds were determined using a pair-wise comparison procedure and sugar solutions with varying concentrations, arranged in ascending order and presented to participants until the lowest detected concentration was noted after three consecutive positive detections, with the median just noticeable difference (JND) value calculated as the population average threshold. Sensory tests were conducted on COVID-19 patients during their infection and recovery periods to evaluate their taste sensation thresholds. The demographic factors of gender, smoking status, BMI, and age group were considered in the analysis.Results A total of 37 patients who met the inclusion criteria of the study were enrolled as participants. Significant variances in sweet detection thresholds were observed among the COVID-19 patients, with consistent decreases over the three testing days, indicating increasing sucrose sensitivity. Infected men showed significant returns to sweet detection thresholds on Day 14 compared to women, while infected smokers exhibited greater recoveries than non-smokers. Overweight patients had consistently elevated thresholds and recovery rates that were comparable to those of normal-weight patients by Day 14, while younger patients had lower thresholds than their older counterparts. On Day 14, the thresholds had significantly recovered to a level comparable to that of healthy individuals (approximately 0.23%).Conclusion These findings suggest that sweet detection thresholds can be used as a marker for assessing the progression and recovery of COVID-19 patients. These findings highlight the importance of recognizing and managing alterations in sweet detection thresholds promptly in COVID-19 patients, as this could positively impact dietary management, nutritional recommendations, and interventions during infection and recovery periods.
dc.identifier.doi10.1371/journal.pone.0309342
dc.identifier.issn1932-6203
dc.identifier.issue8
dc.identifier.pmid39208140
dc.identifier.scopus2-s2.0-85202524174
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0309342
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5193
dc.identifier.volume19
dc.identifier.wosWOS:001304208400070
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPublic Library Science
dc.relation.ispartofPlos One
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectTaste Sensitivity
dc.subjectBody-Weight
dc.subjectPerception
dc.subjectObesity
dc.subjectTemperature
dc.subjectPrevalence
dc.subjectSucrose
dc.titleDetermining the sweet detection threshold of COVID-19 patients during infection and recovery periods
dc.typeArticle

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