West Nile virus seropositivity in Alanya, a coastal city in the Mediterranean region of Turkey

Basit Öğe Kaydı
dc.authorid0000-0002-5612-5051
dc.authorid0000-0002-1225-7693
dc.contributor.authorBektore, Bayhan
dc.contributor.authorDogan, Bora
dc.contributor.authorOzkul, Akyut
dc.contributor.authorGozalan, Aysegul
dc.date.accessioned2026-01-24T12:26:44Z
dc.date.available2026-01-24T12:26:44Z
dc.date.issued2024
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractBACKGROUND: West Nile virus (WNV)-related illness is a global health problem. Understanding the seropositivity rates and identifying the risk factors related to WNV in various animal species including humans is crucial for the implementation of effective prevention strategies. OBJECTIVES: Assess the rate of seropositivity and the risk factors as-sociated with WNV seropositivity .DESIGN: Descriptive, cross-sectional SETTING: Microbiology and virology departments in a veterinary college PATIENTS AND METHODS: In a sample of healthy human participants in Alanya, located close to regions where WNV activity has been detected, anti-WNV IgG antibody detection was performed using enzyme-linked immunosorbent assays. The positive results were con-firmed by virus neutralization tests (VNTs). The sample was compared with a second group of age- and gender-matched healthy subjects selected from a previous cross-sectional study. MAIN OUTCOME MEASURES: Determination of the seropositivity and risk factors that were associated with WNV in healthy humans. SAMPLE SIZE: 87 in current study; 356 in previous study. RESULTS: The first group of 87, which had a high risk of encountering vector mosquitoes, had a positivity rate of 8% (7/87), whereas positivity in the second group was 4.5% (16/356; P=.181). In the entire sample, the anti-WNV IgG antibody was positive in 23 out of 443 (5.2%) sam-ples by the ELISA test. Among these 23 samples, ten were confirmed as positive using VNTs. Therefore, the WNV IgG seropositivity was 2.3% (10/442). Confirmed IgG seropositivity rates were higher among male (3.8%) than female participants (0.9%; P=.054) and among adults aged >= 45 years (4%) than those aged 18-44 years (0.8%; P=.048). CONCLUSION: This study highlights the presence of WNV infection in the research region. More comprehensive and multidisciplinary studies are required to increase our knowledge about this zoonotic infection including risk factors in line with the One Health approach LIMITATIONS: Small sample size.
dc.identifier.doi10.5144/0256-4947.2024.48
dc.identifier.endpage54
dc.identifier.issn0256-4947
dc.identifier.issn1319-9226
dc.identifier.issue1
dc.identifier.pmid38311862
dc.identifier.scopus2-s2.0-85184090863
dc.identifier.scopusqualityQ2
dc.identifier.startpage48
dc.identifier.urihttps://doi.org/10.5144/0256-4947.2024.48
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4885
dc.identifier.volume44
dc.identifier.wosWOS:001163341500003
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherK Faisal Spec Hosp Res Centre
dc.relation.ispartofAnnals of Saudi Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectCentral Anatolia
dc.subjectBlood-Donors
dc.subjectSeroprevalence
dc.subjectSurveillance
dc.subjectCirculation
dc.subjectInfections
dc.titleWest Nile virus seropositivity in Alanya, a coastal city in the Mediterranean region of Turkey
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu