Readmission rates within the first 30 and 90 days after severe COPD exacerbations (RACE study)

Basit Öğe Kaydı
dc.authorid0000-0001-7320-976X
dc.authorid0000-0002-5174-6457
dc.authorid0000-0001-8394-6544
dc.authorid0000-0003-4634-205X
dc.contributor.authorToprak, Oya Baydar
dc.contributor.authorPolatli, Mehmet
dc.contributor.authorBaha, Ayse
dc.contributor.authorKokturk, Nurdan
dc.contributor.authorYapar, Dilek
dc.contributor.authorOzkan, Secil
dc.contributor.authorSen, Elif
dc.date.accessioned2026-01-24T12:29:00Z
dc.date.available2026-01-24T12:29:00Z
dc.date.issued2024
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractChronic obstructive pulmonary disease (COPD) frequently results in hospital readmission and contributes to increased morbidity and mortality. This multicenter prospective study aimed to identify factors that increase the risk of readmission within 30 to 90 days of severe COPD exacerbation. A total of 415 patients admitted to the emergency department (ED) or general pulmonology ward after discharge due to severe exacerbations from 13 tertiary centers in Turkey were included. Of the participants, 346 (83.4%) were male and 69 (16.6%) were female, with an average age of 69.0 +/- 9.1 years. Readmissions within 30 and 90 days after the initial hospitalization occurred in 176 (42.4%) and 191 (46%) patients, respectively. Prospective data collection focused on exacerbation severity, disease severity, and the utility of initial admissions. Factors for 30 to 90 day readmission were analyzed using univariate and multivariate regression models. A 30-day readmission correlated significantly with Hospital Anxiety Depression Scale scores above 16 [odds ratio [OR] 95% confidence intervals [CI]: 1.9 (1.1-3.6); P = .042], severe exacerbation history in the previous year [OR 95% CI: 1.7 (1.1-2.9); P = .038], hospital-acquired pneumonia [OR 95% CI: 1.9 (1-4.1); P = .049)], and frequent antibiotic use in the previous year [OR 95% CI: 1.8 (1.2-2.7); P = .007]. Risk factors for 90-day readmissions included: Grades 3 to 4 tricuspid regurgitation [OR 95% CI: 2.2 (1.1-4.4); P = .024], 2 or more moderate COPD exacerbations [OR 95% CI: 1.9 (1.2-3.1); P = .010], severe exacerbation history in the previous year [OR 95% CI: 2.5 (1.5-4.2); P = .001], immunosuppression [OR 95% CI: 2.7 (1.2-5.7); P = .013], frequent antibiotic use the previous year [OR 95% CI: 1.5 (1-2.4); P = .048], hospitalization via the ED [OR 95% CI: 1.6 (1.1-2.6); P = .028]. To mitigate complications and readmissions, patients with a history of frequent severe COPD exacerbations, high anxiety and depression scores, frequent antibiotic requirements, immunosuppression, tricuspid regurgitation, hospital-acquired pneumonia, and those admitted to the ED should be prioritized for remote monitoring after initial discharge.
dc.description.sponsorshipTurkish Thoracic Society
dc.description.sponsorshipThe authors thank the Turkish Thoracic Society for their contributions and support.
dc.identifier.doi10.1097/MD.0000000000040483
dc.identifier.issn0025-7974
dc.identifier.issn1536-5964
dc.identifier.issue48
dc.identifier.pmid39612431
dc.identifier.urihttps://doi.org/10.1097/MD.0000000000040483
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5048
dc.identifier.volume103
dc.identifier.wosWOS:001367671300029
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofMedicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectantibiotic use
dc.subjectanxiety
dc.subjectCOPD
dc.subjectdepression
dc.subjectexacerbations
dc.subjectimmunosuppression
dc.subjectreadmission
dc.subjectrisk factors
dc.titleReadmission rates within the first 30 and 90 days after severe COPD exacerbations (RACE study)
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu