The Association of Vertebrobasilar System Morphology and Geometry with the Posterior and Anterior Ischemic Stroke

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dc.authorid0000-0001-6870-8177
dc.authorid0000-0001-5789-6985
dc.authorid0000-0002-6789-1296
dc.contributor.authorDemirtas, Ismet
dc.contributor.authorAyran, Aysegul
dc.contributor.authorKus, Koral Caglar
dc.contributor.authorLeblebici, Asim
dc.contributor.authorAyyildiz, Behcet
dc.contributor.authorAliyev, Shamil
dc.contributor.authorAyyildiz, Sevilay
dc.date.accessioned2026-01-24T12:26:47Z
dc.date.available2026-01-24T12:26:47Z
dc.date.issued2025
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractObjective: Morphometric and geometric variations in the vertebrobasilar system (VBS) may influence cerebral hemodynamics, potentially contributing to ischemic strokes in both anterior and posterior circulatory territories. This study aimed to investigate the association between VBS morphology and ischemic stroke localization. Methods: This retrospective observational study analyzed multidetector computed tomography angiography images from 431 patients (187 females, 244 males, mean age: 65.3 +/- 14.6 years). Patients were categorized into three groups: anterior circulation ischemic stroke (ACIS, n=184), posterior circulation ischemic stroke (PCIS, n=88), and control subjects (n=159). Morphometric parameters were assessed using 3D Slicer software. Results: Significant differences in basilar artery (BA) length were observed between stroke groups and controls, with ACIS and PCIS groups exhibiting longer BA lengths (p<0.05). Males had significantly longer vertebral artery (VA) lengths than females in the control and ACIS groups (p value < 0.05). The vertebrobasilar junction angle was significantly wider in females than in males (p value = 0.046). BA bending was predominantly directed to the right across all groups, with no significant differences between the stroke and control groups. VA dominance was more frequent on the left in ACIS and the right in PCIS, while VA hypoplasia was less common in stroke patients compared to controls, contrary to previous reports. Conclusion: While certain morphometric and geometric variations in the VBS were observed, the evidence for a direct association between these characteristics and the localization of ischemic stroke was limited and inconclusive. These findings suggest that vertebrobasilar morphology may not independently determine stroke localization.
dc.identifier.doi10.58600/eurjther2752
dc.identifier.endpage301
dc.identifier.issn2564-7784
dc.identifier.issn2564-7040
dc.identifier.issue5
dc.identifier.startpage289
dc.identifier.trdizinid1355846
dc.identifier.urihttps://doi.org/10.58600/eurjther2752
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1355846
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4937
dc.identifier.volume31
dc.identifier.wosWOS:001567695600001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherPera Yayincilik Hizmetleri
dc.relation.ispartofEuropean Journal of Therapeutics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectvertebrobasilar system
dc.subjecthypoplasia
dc.subjectposterior circulation stroke
dc.subjectanterior circulation stroke
dc.subjectcomputed tomography angiography
dc.titleThe Association of Vertebrobasilar System Morphology and Geometry with the Posterior and Anterior Ischemic Stroke
dc.typeArticle

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