Prognostic Value of Early Treatment Response in Idiopathic Sudden Sensorineural Hearing Loss Treated with Hyperbaric Oxygen

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dc.contributor.authorSevil, Ergun
dc.contributor.authorCebi, Gamze
dc.date.accessioned2026-01-24T12:26:44Z
dc.date.available2026-01-24T12:26:44Z
dc.date.issued2024
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractBackground: The aim of this study is to evaluate the value of early treatment response in predicting the prognosis of patients with idiopathic sudden sensorineural hearing loss (ISSNHL) who received hyperbaric oxygen (HBO) treatment. Methods: A total of 226 patients were available for evaluation and met the inclusion criteria. The patients were separated into 3 groups according to the degree of hearing loss: mild to moderate hearing loss <60 dB, severe hearing loss between 61 dB and 80 dB, and profound hearing loss >= 81 dB. An improvement of >= 10 dB in the pure tone audiogram (PTA) performed after the first 5 sessions compared to the pre-treatment audiogram was considered an early treatment response positive (ETR-P). No improvement or an improvement of <10 dB was considered an early treatment response negative (ETR-N). Results: After the first week of HBO treatment, a total of 119 patients (52.6%) showed ETR-N and 107 patients showed (47.3%) ETR-P. A significant association was found between the degree of hearing loss and ETR-P and ETR-N (Chi(2)= 7.24, P = .02). Patients in the ETR-N group received significantly more HBO sessions than those in the ETR-P group (17.6 +/- 3.4 vs. 13.3 +/- 4.1, P = 0.02). The pure tone average after treatment of the ETR-N patients (60.3) was higher than that of the ETR-P patients (45.2). There was a significant difference between pure tone average after treatment and ETR-P and ETR-N (U = 4110, z = - 4.59, P = .000). Conclusion: Patients who did not achieve sufficient treatment success in the first week of HBO therapy did not achieve good final hearing results.
dc.identifier.doi10.5152/B-ENT.2024.231343
dc.identifier.issn2684-4907
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85212923530
dc.identifier.scopusqualityQ4
dc.identifier.urihttps://doi.org/10.5152/B-ENT.2024.231343
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4887
dc.identifier.volume20
dc.identifier.wosWOS:001382863700004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAves
dc.relation.ispartofB-Ent
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectEarly treatment response
dc.subjecthyperbaric oxygen
dc.subjectinner ear
dc.subjectpure tone audiometry
dc.subjectsensorineural hearing loss
dc.titlePrognostic Value of Early Treatment Response in Idiopathic Sudden Sensorineural Hearing Loss Treated with Hyperbaric Oxygen
dc.typeArticle

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