Investigation of ideal ointment combination to use in septorhinoplasty or nasal flap surgeries

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dc.authorid0000-0003-3602-9289
dc.contributor.authorYildirim, C.
dc.contributor.authorMuluk, N. Bayar
dc.contributor.authorKar, M.
dc.contributor.authorKaya, F.
dc.contributor.authorCingi, C.
dc.date.accessioned2026-01-24T12:29:23Z
dc.date.available2026-01-24T12:29:23Z
dc.date.issued2022
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractOBJECTIVE: We aimed to create an ideal ointment combination to provide fast wound healing with the highest patient comfort after nasal surgery and nasal flap surgery. MATERIALS AND METHODS: Twenty-one male Wistar rats were included. The flap survival method was used. The rats' healing process was evaluated in all groups. After having the same surgical procedure, the following ointments were applied to flap borders twice a day for seven days in each of the groups. In group 1 (Control, n=7), Dexpanthenol 5% (Dex); in group 2, Dex, Ciprofloxacin 0.5 % (Cip) and Ephedrine hydrochloride 1% (Eph); in group 3, Dex+Cip+Eph and Ketoprofen 2.5% (Ket) was applied. On the seventh postoperative day, the size of the necrosis on the flap was evaluated. RESULTS: Median necrotic areas on skin flaps were 36.00% sq mm in group 1, 23.00% sq mm in group 2, and 5.00% sq mm in group 3. Flap necrosis areas on skin flaps were group 3
dc.identifier.doi10.26355/eurrev_202212_30476
dc.identifier.endpage14
dc.identifier.issn1128-3602
dc.identifier.pmid36524906
dc.identifier.startpage9
dc.identifier.urihttps://doi.org/10.26355/eurrev_202212_30476
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5327
dc.identifier.volume26
dc.identifier.wosWOS:000911202200002
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260121
dc.subjectFlap necrosis
dc.subjectrat
dc.subjectDexpantenol
dc.subjectCiprofloxacin
dc.subjectEphedrine hydrochloride
dc.subjectKetoprofen
dc.titleInvestigation of ideal ointment combination to use in septorhinoplasty or nasal flap surgeries
dc.typeArticle

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