An International Delphi Consensus on Diagnostic Criteria for Buerger's Disease

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dc.contributor.authorFazeli, Bahare
dc.contributor.authorPoredoš, Pavel
dc.contributor.authorSchernthaner, Gerit Holger
dc.contributor.authorStephen, Edwin
dc.contributor.authorKozak, Matija
dc.contributor.authorCatalano, Mariella
dc.contributor.authorPécsvárady, Zsolt
dc.date.accessioned2026-01-24T12:20:44Z
dc.date.available2026-01-24T12:20:44Z
dc.date.issued2022
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractBackground: Buerger's disease (BD) remains a debilitating condition. Despite multiple published diagnostic criteria for BD, none is universally accepted as a gold standard. Methods: We conducted a 2-round modified Delphi consensus study to establish a consensus on the diagnostic. The questionnaire included statements from several commonly used diagnostic criteria for BD. Qualitative and quantitative analysis methods were performed. An agreement level of 70% was applied. Results: Twenty nine experts from 18 countries participated in this study. Overall, 75 statements were circulated in Round 1. Of these, 28% of statements were accepted. Following comments, 21 statements were recirculated in Round 2 and 90% were accepted. Although more than 90% of the experts did not agree that the diagnosis of BD can be based only on clinical manifestation, none of the nonclinical manifestations of BD were agreed as a part of the diagnostic criteria. There was an agreement that a history of tobacco consumption in any form, not necessarily confined to the current use, should be a part of the diagnostic criteria of BD. The history of thrombophlebitis migrans, even if not present at presentation, was accepted as a clue for BD diagnosis. It was also agreed that discoloration of the toes or fingers could be included in the diagnostic criteria of BD. Experts agreed that histology results could differentiate BD from atherosclerosis obliterans and other types of vasculitis. The presence of corkscrew collaterals on imaging and burning pain reached the agreement at the first round but not at the second. There was no consensus regarding age cut-off, the requirement of normal lipid profile, and normal blood glucose for BD diagnosis. Conclusions: The present study demonstrated discrepancies in the various published diagnostic criteria for BD and their selective utilization in routine clinical practice worldwide. We propose that all published diagnostic criteria for BD be re-evaluated for harmonization and universal use. © 2022
dc.identifier.doi10.1016/j.avsg.2022.03.028
dc.identifier.endpage218
dc.identifier.issn0890-5096
dc.identifier.pmid35398199
dc.identifier.scopus2-s2.0-85130963506
dc.identifier.scopusqualityQ2
dc.identifier.startpage211
dc.identifier.urihttps://doi.org/10.1016/j.avsg.2022.03.028
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4547
dc.identifier.volume85
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Inc.
dc.relation.ispartofAnnals of Vascular Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20260121
dc.subjectantinuclear antibody
dc.subjectbeta2 glycoprotein 1 antibody
dc.subjectC reactive protein
dc.subjectcentromere antibody
dc.subjectglucose
dc.subjecthigh density lipoprotein cholesterol
dc.subjectneutrophil cytoplasmic antibody
dc.subjectscl 70 antibody
dc.subjectlipid
dc.subjectankle brachial index
dc.subjectArticle
dc.subjectatherosclerotic plaque
dc.subjectBuerger disease
dc.subjectcannabis use
dc.subjectclinical feature
dc.subjectconsensus development
dc.subjectcurrent smoker
dc.subjectDelphi study
dc.subjectdemographics
dc.subjectdiabetes mellitus
dc.subjectduplex Doppler ultrasonography
dc.subjectdyslipidemia
dc.subjecterythrocyte sedimentation rate
dc.subjectfemale
dc.subjectglucose blood level
dc.subjecthepatitis B
dc.subjecthepatitis C
dc.subjecthigh density lipoprotein cholesterol level
dc.subjecthistopathology
dc.subjecthuman
dc.subjectHuman immunodeficiency virus infection
dc.subjecthypercoagulability
dc.subjecthyperlipidemia
dc.subjecthyperpigmentation
dc.subjectlaboratory test
dc.subjectmale
dc.subjectnon-smoker
dc.subjectpassive smoking
dc.subjectperipheral occlusive artery disease
dc.subjectperipheral vein
dc.subjectqualitative analysis
dc.subjectquantitative analysis
dc.subjectquestionnaire
dc.subjectsocial status
dc.subjectsyphilis
dc.subjectthrombophlebitis migrans
dc.subjecttobacco consumption
dc.subjectupper limb
dc.subjectvasculitis
dc.subjectvasospasm
dc.subjecttreatment outcome
dc.subjectBlood Glucose
dc.subjectDelphi Technique
dc.subjectHumans
dc.subjectLipids
dc.subjectThromboangiitis Obliterans
dc.subjectTreatment Outcome
dc.titleAn International Delphi Consensus on Diagnostic Criteria for Buerger's Disease
dc.typeArticle

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