Evaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes’ Competitive Performance

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dc.contributor.authorBulgay, Celal
dc.contributor.authorBayraktar, Işık
dc.contributor.authorKazan, Hasan Hüseyin
dc.contributor.authorYıldırım, Damla Selin
dc.contributor.authorZorba, Erdal
dc.contributor.authorAkman, Onur
dc.contributor.authorErgun, Mehmet Ali
dc.contributor.authorCerit, Mesut
dc.contributor.authorUlucan, Korkut
dc.contributor.authorEken, Özgür
dc.contributor.authorCeylan, Halil İbrahim
dc.contributor.authorBadicu, Georgian
dc.date.accessioned2023-07-31T13:09:19Z
dc.date.available2023-07-31T13:09:19Z
dc.date.issued2023
dc.departmentALKÜ, Fakülteler, Spor Bilimleri Fakültesi, Antrenörlük Eğitimi Bölümü
dc.description.abstractThe present study aimed to examine the vitamin D receptor (VDR), rs2228570 polymorphism, and its effect on elite athletes’ performance. A total of 60 elite athletes (31 sprint/power and 29 endurance) and 20 control/ physically inactive, aged 18–35, voluntarily participated in the study. The International Association of Athletics Federations (IAAF) score scale was used to determine the performance levels of the athletes’ personal best (PB). Whole exome sequencing (WES) was performed by the genomic DNA isolated from the peripheral blood of the participants. Sports type, sex, and competitive performance were chosen as the parameters to compare within and between the groups by linear regression models. The results showed no statistically significant difference between the CC, TC, and TT genotypes within and between the groups (p > 0.05). Additionally, our results underlined that there were no statistically significant differences for the association of rs2228570 polymorphism with PBs within the groups of the (p > 0.05) athletes. The genetic profile in the selected gene was similar in elite endurance, sprint athletes, and in controls, suggesting that rs2228570 polymorphism does not determine competitive performance in the analyzed athlete cohort. © 2023 by the authors.
dc.identifier.doi10.3390/healthcare11050681
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85149708053&origin=resultslist&sort=plf-f&src=s&nlo=&nlr=&nls=&sid=20c4fe371b9b908d4f7e419f791331ff&sot=aff&sdt=cl&cluster=scofreetoread%2c%22all%22%2ct&sl=72&s=AF-ID%28%22Alanya+Alaaddin+Keykubat+University%22+60198720%29+AND+SUBJAREA%28MEDI%29&relpos=13&citeCnt=0&searchTerm=
dc.identifier.urihttps://hdl.handle.net/20.500.12868/2328
dc.identifier.urihttps://www.mdpi.com/2227-9032/11/5/681
dc.identifier.volume11en_US
dc.indekslendigikaynakScopus
dc.language.isoen
dc.relation.ispartofHealthcare (Switzerland)
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectathletics; sprint/power athletes; endurance athletes; VDR; rs2228570 polymorphism
dc.subjectAthletics
dc.subjectSprint/power athletes
dc.subjectEndurance athletes
dc.subjectVDR
dc.subjectrs2228570 polymorphism
dc.titleEvaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes’ Competitive Performance
dc.typeArticle

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