Role of Fatty Acid Chemical Structures on Underlying Mechanisms of Neurodegenerative Diseases and Gut Microbiota

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dc.authorid0000-0002-7248-7933
dc.contributor.authorKocanci, Fatma Gonca
dc.date.accessioned2026-01-24T12:30:49Z
dc.date.available2026-01-24T12:30:49Z
dc.date.issued2021
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractNeurodegenerative diseases have been found to be closely related to common mechanisms such as protein aggregation, neural oxidative stress, neuroinflammation, mitochondrial dysfunction, and gut microbiota dysbiosis. Although there are some drugs that can temporarily reduce symptoms, there is no cure for these diseases. Therefore, the discovery of molecules that can halt the pathology of these diseases is urgently needed in the present time. Fatty acids show positive effects on the pathology of neurodegenerative diseases, depending on the degree of unsaturation and the shortness of the hydrocarbon chain. Understanding the effects of different structures of fatty acids on the underlying mechanisms of neurodegenerative diseases and the balance of gut microbiota can produce positive implications for the development of future treatments. The present review focuses on the role of different fatty acids on underlying mechanisms of neurodegenerative diseases, gut microbiota balance, and gut-brain axis.
dc.identifier.doi10.1002/ejlt.202000341
dc.identifier.issn1438-9312
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85102246879
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1002/ejlt.202000341
dc.identifier.urihttps://hdl.handle.net/20.500.12868/5451
dc.identifier.volume123
dc.identifier.wosWOS:000625984400001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofEuropean Journal of Lipid Science and Technology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260121
dc.subjectfatty acids’ structures
dc.subjectgut microbiota
dc.subjectneurodegenerative diseases
dc.titleRole of Fatty Acid Chemical Structures on Underlying Mechanisms of Neurodegenerative Diseases and Gut Microbiota
dc.typeReview Article

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