Does Lactate Dehydrogenase Act as an Early Warning System Predicting Mortality in Trauma Patients?

Basit Öğe Kaydı
dc.contributor.authorCanakci, Selcuk Eren
dc.contributor.authorTurkdogan, Figen Tunali
dc.contributor.authorTurkmen, Fatih
dc.contributor.authorTurkdogan, Kenan Ahmet
dc.contributor.authorKapci, Mucahit
dc.contributor.authorKucukgul, Furkan
dc.date.accessioned2026-01-24T12:26:41Z
dc.date.available2026-01-24T12:26:41Z
dc.date.issued2025
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractAim: Trauma is one of the most prevalent causes of death and disability in middle age, and early diagnosis and treatment are critical in minimizing mortality and morbidity. Lactate dehydrogenase (LDH) is an indicator of inflammation in many diseases. We aim to present this study, in which we measure the power of LDH to show us mortality in the blood sample taken at the first examination in trauma patients, in the light of the literature. Materials and Methods: Trauma patients of emergency medicine department between November 2020 and November 2021, were analyzed. Trauma mechanism, consultations, mortality-morbidity, and scoring were evaluated retrospectively. Results: The glasgow coma scale (GCS), injury severity score (ISS), and new injury severity score (NISS) values of the patients were 14.58 +/- 1.76 (95% confidence interval: 14.43-14.73), 14 (0-76), and 18 (0-101) respectively. The data for leukocytes, hemoglobin, platelets, glucose, aspartate aminotransferase (AST), and LDH were significantly different between the control and patient groups. The comparison of leukocyte, hemoglobin, glucose, creatinine, AST, and LDH data between the survivors and the deceased in the patient group revealed a statistically significant difference. ROC analysis was then applied to evaluate these markers in the non-surviving patients. ISS, NISS, GCS, alanine aminotransferase, AST and LDH were found to be significant. Conclusion: LDH elevation, which is studied between routine procedures, may be beneficial for physicians working in the periphery both in patient referral and in making an early operation decision. Thus, we believe that mortality and morbidity will decrease with the use of LDH, a cost-effective marker.
dc.identifier.doi10.4274/eajem.galenos.2025.80008
dc.identifier.endpage292
dc.identifier.issn2149-5807
dc.identifier.issn2149-6048
dc.identifier.issue4
dc.identifier.startpage287
dc.identifier.urihttps://doi.org/10.4274/eajem.galenos.2025.80008
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4856
dc.identifier.volume24
dc.identifier.wosWOS:001645515400001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofEurasian Journal of Emergency Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectTrauma
dc.subjectLDH
dc.subjectradiology
dc.subjectmortality
dc.subjectemergency service
dc.titleDoes Lactate Dehydrogenase Act as an Early Warning System Predicting Mortality in Trauma Patients?
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu