Nazofaringeal kanserlerde prognostik faktörlerin değerlendirilmesi
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Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Alanya Alaaddin Keykubat Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Kliniğimizde teşhisve tedavi edilen nazofaringeal kanserli (NPC) hastaların hayatta kalmasınıetkileyen prognostik faktörleri incelemektir.Yöntemler: Kliniğimizde2009-2013 yılları arasında teşhis ve tedavi edilen nazofaringeal kanserlihastalar geriye dönük olarak incelendi.Bulgular: Çalışmamızda 33hasta erkek (% 73.3), 12 hasta kadın (% 26.6), erkek / kadın oranı 2.75 idi.Ortalama yaş 50,8; En genç hasta 14 ve en yaşlısı 84 yaşında idi. En sıkgörülen neden servikal lenf nodu metastazı (% 66,7) idi. Hastalarımızın%66,6'sında ileri evre tümör vardı (Evre 3-4). Düşük T evresi hastalarında dahauzun sağkalım süresi saptanırken, N-evresi ile sağkalım arasında ilişkisaptanmadı. Histopatolojik tiplerle 2 yıllık sağkalım arasında istatistikselolarak bir ilişki saptanmadı. Genç yaş grubu ve erkek hastalarda daha uzunsağkalım süresi gözlemlendi fakat bu istatistiksel olarak anlamlı değildi.Sonuç: Genç yaş iyiprognostik faktörlerdir, ancak tanıdaki ilerlemiş T ve N evreleri kötüprognostik faktörlerdir. Bu nedenle erken teşhis, tedavi ve sağkalım açısındanönemlidir.
Aim: We aimed to examineprognostic factors that affect the survival of patients with nasopharyngealcancer (NPC) who were diagnosed and treated in our clinic. Methods: Patients withnasopharyngeal cancer, who were diagnosed and treated in our clinic between 2009-2013,were examined retrospectively. Results: In our study, 33patients were male (%73.3), 12 patients were female (%26.6), and male/female ratio was 2.75. Mean age was50,8; the youngest patient was 14 and the oldest one was 84 years old. The most common presenting cause was cervicallymph node metastasis (%66,7). %66,6 of our patients had advanced stage tumor(Stage 3-4). Longer survival was detected in low T-stage patients, whereas norelation was determined between N-stage and survival. No statistical relationwas determined between histopathological types and 2-year survival. Longersurvival was observed in young age group and male patients; however, this wasnot statistically significant.Conclusion: Younger age are goodprognostic factors, however, the advanced T and N stages at diagnosis are poorprognostic factors. Therefore, early diagnosis is important in terms oftreatment and survival.
Aim: We aimed to examineprognostic factors that affect the survival of patients with nasopharyngealcancer (NPC) who were diagnosed and treated in our clinic. Methods: Patients withnasopharyngeal cancer, who were diagnosed and treated in our clinic between 2009-2013,were examined retrospectively. Results: In our study, 33patients were male (%73.3), 12 patients were female (%26.6), and male/female ratio was 2.75. Mean age was50,8; the youngest patient was 14 and the oldest one was 84 years old. The most common presenting cause was cervicallymph node metastasis (%66,7). %66,6 of our patients had advanced stage tumor(Stage 3-4). Longer survival was detected in low T-stage patients, whereas norelation was determined between N-stage and survival. No statistical relationwas determined between histopathological types and 2-year survival. Longersurvival was observed in young age group and male patients; however, this wasnot statistically significant.Conclusion: Younger age are goodprognostic factors, however, the advanced T and N stages at diagnosis are poorprognostic factors. Therefore, early diagnosis is important in terms oftreatment and survival.
Açıklama
Anahtar Kelimeler
nazofarenks, prognostik faktörler, retrospektif, Nasopharynx, Prognostic factors, Retrospective
Kaynak
Acta Medica Alanya
WoS Q Değeri
Scopus Q Değeri
Cilt
1
Sayı
2
