The association of non-motor symptoms with motorsymptoms in parkinson’s disease
| dc.contributor.author | Çankaya, Şeyda | |
| dc.date.accessioned | 2022-11-30T05:46:21Z | |
| dc.date.available | 2022-11-30T05:46:21Z | |
| dc.date.issued | 2021 | |
| dc.department | ALKÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | |
| dc.description.abstract | Aim: Idiopathic Parkinson’s disease (IPD) is the second most common progressive neurodegenerative disorder and well known with typical motor impairment. Besides motor symptoms, non-motor symptoms (NMS) occur very frequently among patients with IPD. This study aims to assess the presence of non-motor symptoms with the severity of motor symptoms.Materials and Methods: Alaaddin Keykubat University Training and Research Hospital’s database has been screened for identifying patients with IPD from 2015-2019. The patients’ motor symptom, NMS, and Hoehn & Yahr stage (H&Y stage) were assessed with the Movement Disorder Society - Unified Parkinson’s Disease Rating Scale (MDS-UPDRS).Results: A total of 50 IPD patients were analyzed. Analysis by NMS part of MDS-UPDRS (Part I) showed that NMS was present in 99.7% of patients. NMS part score was positively correlated with H&Y stages and total motor scores of MDS-UPDRS (part II-III). The most common symptoms were pain (84%), daytime sleepiness (78%), and urinary problems (76%). Significantly, there was an association between motor impairment, H&Y, and the following NMS items; hallucinations/psychosis, depressed mood, daytime sleepiness, urinary problems, constipation, light-headedness on standing, and fatigue (p<0.05, Spearman’s rho). Conclusions: Considering our data suggested that almost all patients with PD experience NMS. NMS are mostly worsened with exacerbation of MS (motor symptoms) and H&Y in cases. These findings will help understand the clinical aspect of PD and may improve personalized medicine and research in PD. | |
| dc.identifier.doi | 10.5455/annalsmedres.2021.03.271 | |
| dc.identifier.endpage | 1582 | en_US |
| dc.identifier.issue | 8 | en_US |
| dc.identifier.startpage | 1577 | en_US |
| dc.identifier.uri | https://search.trdizin.gov.tr/yayin/detay/459554/the-association-of-non-motor-symptoms-with-motorsymptoms-in-parkinsons-disease | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12868/2069 | |
| dc.identifier.volume | 28 | en_US |
| dc.indekslendigikaynak | TR-Dizin | |
| dc.language.iso | tr | |
| dc.relation.ispartof | Annals of Medical Research | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Idiopathic Pankinson's Disease | |
| dc.subject | MDS-UPDRS | |
| dc.subject | Motor Symptoms | |
| dc.subject | Non-Motor Symptoms | |
| dc.title | The association of non-motor symptoms with motorsymptoms in parkinson’s disease | |
| dc.type | Article |
