Does augmentation with antipsychotic agents affect the medication adherence of the child with obsessive-compulsive disorder?

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dc.contributor.authorKara, Tayfun
dc.contributor.authorYılmaz, Semra
dc.contributor.authorKınay, Duygu
dc.contributor.authorAkaltun, İsmail
dc.date.accessioned2021-02-19T21:29:24Z
dc.date.available2021-02-19T21:29:24Z
dc.date.issued2019
dc.departmentALKÜ
dc.description.abstractAntipsychotic agents can be used for augmentation when the response to treatment is insufficient in children with obsessive compulsive disorder. Our aim was to investigate adherence to treatment between patients with and without antipsychotic augmentation and factors potentially related to this. One hundred fourteen children and adolescents aged 8-18 years diagnosed with OCD and still receiving treatment were included in the study. Fifty-two subjects were received antipsychotic therapy for augmentation, while 62 were not receiving it. All subjects were evaluated using a sociodemographic data form, the 8-item Morisky Medication Adherence Scale (MMAS-8), and the Udvalg for Klinikse Undersegelser (UKU) side-effects rating scale. The results were then subjected to statistical analysis. Total MMAS-8 scores were statistically significantly lower in the augmentation group than in the monotherapy group (p: 0.01). Sex, receipt of psychotherapy and family monitoring of treatment had no effect on total MMAS-8 scores (p: 0.949, p: 0.394, and p: 0.198, respectively). Higher UKU side-effect rating scale scores were determined in the augmentation group compared to the monotherapy group (p<0.05). Correlation analysis revealed that UKU total score (r:-0.272, p:0.003) and UKU psychological side-effects subscale score (r:-0.263, p:0.005) were significantly inversely correlated with MMAS-8 total scores. Side-effects deriving from medications affected adherence to treatment more significantly than several other environmental factors in children with OCD. Our findings show the need for side-effects, and particularly psychological side-effects, the frequency of which increases with augmentation, to be monitored in terms of adherence to treatment.
dc.identifier.doi10.5455/medscience.2018.07.8944
dc.identifier.endpage202en_US
dc.identifier.issn2147-0634
dc.identifier.issn2147-0634
dc.identifier.issue1en_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://doi.org/10.5455/medscience.2018.07.8944
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpBNE5EWTBOQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12868/1062
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthor0-belirlenecek
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Eleman
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiyoloji
dc.subjectAlerji
dc.subjectAnatomi ve Morfoloji
dc.subjectAndroloji
dc.subjectAnestezi
dc.subjectOdyoloji ve Konuşma-Dil Patolojisi
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.subjectBiyofizik
dc.subjectBiyoteknoloji ve Uygulamalı Mikrobiyoloji
dc.subjectKalp ve Kalp Damar Sistemi
dc.subjectHücre Biyolojisi
dc.subjectKlinik Nöroloji
dc.subjectYoğun Bakım, Tıp
dc.subjectDermatoloji
dc.subjectAcil Tıp
dc.subjectEndokrinoloji ve Metabolizma
dc.subjectGastroenteroloji ve Hepatoloji
dc.subjectGeriatri ve Gerontoloji
dc.subjectSağlık Bilimleri ve Hizmetleri
dc.subjectHematoloji
dc.subjectİmmünoloji
dc.subjectEnfeksiyon Hastalıkları
dc.subjectTamamlayıcı ve Entegre Tıp
dc.subjectTıbbi Etik
dc.subjectTıbbi İnformatik
dc.subjectTıbbi Laboratuar Teknolojisi
dc.subjectGenel ve Dahili Tıp
dc.subjectAdli Tıp
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectMikrobiyoloji
dc.subjectNörolojik Bilimler
dc.subjectKadın Hastalıkları ve Doğum
dc.subjectOnkoloji
dc.subjectGöz Hastalıkları
dc.subjectOrtopedi
dc.subjectKulak, Burun, Boğaz
dc.subjectPatoloji
dc.subjectPediatri
dc.subjectPeriferik Damar Hastalıkları
dc.subjectFizyoloji
dc.subjectTemel Sağlık Hizmetleri
dc.subjectPsikiyatri
dc.subjectHalk ve Çevre Sağlığı
dc.subjectRadyoloji, Nükleer Tıp, Tıbbi Görüntüleme
dc.subjectRehabilitasyon
dc.subjectSolunum Sistemi
dc.subjectRomatoloji
dc.subjectSpor Bilimleri
dc.subjectCerrahi
dc.subjectTransplantasyon
dc.subjectTropik Tıp
dc.subjectÜroloji ve Nefroloji
dc.titleDoes augmentation with antipsychotic agents affect the medication adherence of the child with obsessive-compulsive disorder?
dc.typeArticle

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