Elektif Cerrahi Uygulanan Obez Kadın Hastalarda Sugammadeks ve Neostigminin Yaşa Bağlı Etkinlik ve Maliyetinin Retrospektif Olarak Karşılaştırılması
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Tarih
2024
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Yayıncı
Alanya Alaaddin Keykubat Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Çalışmanın amacı, obez, genç-yaşlı hastalarda sugammadeks ve neostigminin klinik etkisini ve maliyetini karşılaştırmaktır. Gereç ve Yöntemler: Bu çalışmada, ameliyat süresi 150 dakikayı geçmeyen ve kas gevşetici olarak rokuronyum kullanılan hastaların tıbbi ve anestezi kayıtları retrospektif olarak değerlendirildi. Dosyaları incelenen hastalar yaş ve verilen ilaca göre 4 gruba ayrıldı; Grup YS: 20-60 yaş arası 2mg/kg sugammadeks, Grup ES: 60-80 yaş arası 2mg/kg sugammadeks, Grup YN: 20-60 yaş arası 0,04 mg/kg neostigmin + 0,01 mg/kg atropin, Grup EN: 60-80 yaş arası 0,04 mg/kg neostigmin + 0,01 mg/kg atropin. TOF 25,75,90 zamanı, derlenme skorları hastaların anestezi kayıtlarından kaydedildi. Bulgular: TOF 25,75,90'a ulaşma süreleri açısından Grup YS ve Grup ES'deki hastaların Grup YN ve Grup EN'ye göre daha hızlı TOF değerlerine ulaştığı görüldü. (p<0,05). Neostigmin ile karşılaştırıldığında, aynı yaş grubunda sugammadeks verilen hastaların daha hızlı iyileşme süresine sahip olduğu ve istatistiksel olarak anlamlı farklılıklar olduğu bulundu (p<0,05). Sonuç: Sugammadeks, neostigmine göre orta dereceli nöromüsküler bloğun hızlı ve etkili geri dönüşümünü sağlamakla birlikte, çok düşük yan etki insidansına ve daha hızlı iyileşme sürelerine sahiptir.
Aim: The purpose of the study is to compare the clinical impact and cost of sugammadex and neostigmine in obese, young-elderly patients. Materials and Methods: In this study, the medical and anesthesia records of patients whose operation did not exceed 150 minutes and who used rocuronium as a muscle relaxant were evaluated retrospectively. Patients whose files were examined were divided into 4 groups according to age and drug given; Group YS: 2 mg/kg sugammadex between 20–60 years, Group ES: 2 mg/kg sugammadex between 60-80years, Group YN: 0.04 mg/kg neostigmin + 0.01 mg/kg atropine between 20–60 years, Group EN: 0.04 mg/kg neostigmin + 0.01 mg/kg atropine between 60–80 years. Time of TOF 25, 75, 90 recovery scores were recorded from the anesthesia records of the patients. Results: Regarding the time to reach TOF 25,75,90, it was seen that the patients in Group YS and Group ES reached faster TOF values than Group YN and Group EN ( p<0,05). Compared with neostigmine, patients who were given sugammadex in the same age group were found to have faster recovery time and statistically significant differences (p<0,05). Conclusion: Sugammadex provides rapid and effective reversal of moderate neuromuscular block compared to neostigmine, with a very low incidence of side effects and faster recovery times.
Aim: The purpose of the study is to compare the clinical impact and cost of sugammadex and neostigmine in obese, young-elderly patients. Materials and Methods: In this study, the medical and anesthesia records of patients whose operation did not exceed 150 minutes and who used rocuronium as a muscle relaxant were evaluated retrospectively. Patients whose files were examined were divided into 4 groups according to age and drug given; Group YS: 2 mg/kg sugammadex between 20–60 years, Group ES: 2 mg/kg sugammadex between 60-80years, Group YN: 0.04 mg/kg neostigmin + 0.01 mg/kg atropine between 20–60 years, Group EN: 0.04 mg/kg neostigmin + 0.01 mg/kg atropine between 60–80 years. Time of TOF 25, 75, 90 recovery scores were recorded from the anesthesia records of the patients. Results: Regarding the time to reach TOF 25,75,90, it was seen that the patients in Group YS and Group ES reached faster TOF values than Group YN and Group EN ( p<0,05). Compared with neostigmine, patients who were given sugammadex in the same age group were found to have faster recovery time and statistically significant differences (p<0,05). Conclusion: Sugammadex provides rapid and effective reversal of moderate neuromuscular block compared to neostigmine, with a very low incidence of side effects and faster recovery times.
Açıklama
Anahtar Kelimeler
Anaesthesiology, Anesteziyoloji
Kaynak
Acta Medica Alanya
Acta Medica Alanya
Acta Medica Alanya
WoS Q Değeri
Scopus Q Değeri
Cilt
8
Sayı
3
