Serial measurement of soluble endoglin for risk assessment at the diagnosis of fetal growth restriction

dc.contributor.authorErol Deniz, Merve
dc.contributor.authorDeniz, Alparslan
dc.contributor.authorMendilcioğlu, İnanç
dc.contributor.authorSanhal, Cem Yaşar
dc.contributor.authorÖzdem, Sebahat
dc.contributor.authorKüçükçetin, İkbal Özen
dc.contributor.authorKandemir, Hülya
dc.date.accessioned2023-11-30T06:41:17Z
dc.date.available2023-11-30T06:41:17Z
dc.date.issued2021
dc.departmentALKÜ, Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractAim: In this study, we aimed to investigate the soluble endoglin (sEng) levels in pregnant women with fetal growth restriction (FGR) and to examine the possible relation of the sEng levels with the time remaining to delivery and maternal and fetal complications. Methods: A total of 42 pregnant women diagnosed with FGR were retrospectively reviewed. Using the maternal blood samples it is at the collected 24-37 gestational weeks, the sEng levels were measured. Fetal biometry measurements, umbilical artery, uterine artery, middle cerebral artery Doppler indices were documented. Results: Of all patients, 17 (40%) were diagnosed with early-onset FGR, while 25 (60%) were diagnosed with late-onset FGR. Abnormal Doppler findings were present in 25 (60%) patients. Of 42 newborns, 18 (42%) were hospitalised in the neonatal unit. The mean sEng level calculated by taking the average of the first and second blood samples was 63.24 ± 49.83 ng/mL. There was no statistically significant difference in the mean sEng levels between those who gave birth within four, three, and two weeks after the diagnosis of FGR and those who did not. There was a positive significant correlation between the mean sEng levels and systolic blood pressure (r = 0.319, P =.04). Conclusions: We did not find a statistically significant relationship between the sEng level and the time remaining to the time of delivery in pregnant women with FGR. We found no statistically significant difference in sEng level between the groups in pregnant women with fetuses with FGR with or without maternal and fetal complications.
dc.identifier.doi10.1111/ijcp.14840
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85115306087&origin=resultslist&sort=plf-f&src=s&nlo=&nlr=&nls=&sid=20c4fe371b9b908d4f7e419f791331ff&sot=aff&sdt=cl&cluster=scofreetoread%2c%22all%22%2ct&sl=72&s=AF-ID%28%22Alanya+Alaaddin+Keykubat+University%22+60198720%29+AND+SUBJAREA%28MEDI%29&relpos=98&citeCnt=1&searchTerm=
dc.identifier.urihttps://hdl.handle.net/20.500.12868/2436
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/pdf/10.1111/ijcp.14840?getft_integrator=scopus&utm_source=scopus
dc.indekslendigikaynakScopus
dc.language.isoen
dc.relation.ispartofInternational Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titleSerial measurement of soluble endoglin for risk assessment at the diagnosis of fetal growth restriction
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Int J Clinical Practice - 2021 - Erol Deniz - Serial measurement of soluble endoglin for risk assessment at the diagnosis.pdf
Boyut:
542.56 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin // Full Text
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama: