The Effect of Regularly Performed Oderate-Intensity Exercise Program on Thiol/Disulfide Homeostasis, and Ischemia-Modified Albumin
| dc.contributor.author | Pala, Mukaddes | |
| dc.contributor.author | Altan, Mehmet | |
| dc.contributor.author | Hanikoğlu, Ferahat | |
| dc.contributor.author | Neşelioğlu, Salim | |
| dc.contributor.author | Erel, Özcan | |
| dc.contributor.author | Metin, Gökhan | |
| dc.date.accessioned | 2022-10-03T08:12:20Z | |
| dc.date.available | 2022-10-03T08:12:20Z | |
| dc.date.issued | 2022 | |
| dc.department | ALKÜ, Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü | |
| dc.description.abstract | Aim: Thiol/disulfide homeostasis is an indicator of oxidative stress and antioxidant capacity. Ischemia-modified albumin (IMA) is an important marker for both oxidative stress and ischemia. We aimed to evaluate the possible effects of regularly performed moderate-intensity exercise on thiol/disulfide homeostasis, and IMA levels. Methods: Sprague Dawley rats were used. The study was composed of an Exercise group (EG, n=9) and Control group (CG, n=6). A 10-weeks swimming exercise was performed. Thiol/disulfide homeostasis measurement method was used in this study. IMA levels were measured by a cobalt-albumin binding method. Results: In the EG, total thiol levels were significantly higher compared to the CG (p<0.01). The disulfide/total thiol ratio was lower in the EG compared to the CG (p<0.01). We observed that there was a slight increase in IMA levels in EG (p=0.18). This increase was not statistically significant. Conclusion: Regularly performed moderate-intensity exercise has increased native and total thiol levels. Increase of thiol levels can prevent oxidative stress. Regularly performed moderate-intensity exercise programs appear to provide favourable effects on oxidative stress. | |
| dc.identifier.doi | 10.30565/medalanya.1055424 | |
| dc.identifier.endpage | 125 | en_US |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.startpage | 120 | en_US |
| dc.identifier.uri | https://dergipark.org.tr/tr/download/article-file/2182572 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12868/1761 | |
| dc.identifier.volume | 6 | en_US |
| dc.language.iso | en | |
| dc.relation.ispartof | Acta Medica Alanya | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Swimming | |
| dc.subject | Oxidative stress | |
| dc.subject | Thiol/disulfide homeostasis | |
| dc.subject | Ischemiamodified albumin | |
| dc.title | The Effect of Regularly Performed Oderate-Intensity Exercise Program on Thiol/Disulfide Homeostasis, and Ischemia-Modified Albumin | |
| dc.type | Article |
