Trace Elements (Zn and Cu) and Oxidative Stress in Pediatric Patients with Persistent Allergic Rhinitis

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dc.contributor.authorGünizi, Hüseyin
dc.contributor.authorSavaş, Hasan Basri
dc.contributor.authorGenç, Sibel
dc.date.accessioned2024-10-24T11:22:45Z
dc.date.available2024-10-24T11:22:45Z
dc.date.issued2022
dc.departmentALKÜ
dc.description.abstractObjective: To investigate the relationship between complaints and serum trace elements and oxidative stress levels in pediatric patients with allergic rhinitis (AR). Study design: Descriptive study. Place and duration of study: Department of Otolaryngorhinology, Medicine Faculty, Alanya Alaaddin Keykubat University, between May and September 2020. Methodology: Thirty-five patients diagnosed with AR in the pediatric age group and 35 healthy control groups were examined. The patients were evaluated according to the ARIA (Allergic rhinitis and its ımpact on asthma) guidelines. Blood samples were taken during the attack to measure serum Zn and Cu levels and oxidative stress levels from patients diagnosed with AR. Measurements of serum Zinc and Copper levels, and recently developed new generation oxidant-antioxidant balance markers were performed spectrophotometrically using a commercial kit.] Results: The mean ages of the study patients and healthy controls were 10.9 ± 4.7 and 10.5 ± 4.9 years, respectively. Female/Male ratio was 20 (57.1%)/15 (42.9%) in both groups. Zn level was lower in the patient group (p <0.05). Total thiol and native thiol values were higher in the control group (p <0.05). Statistically significant high disulfide values were found in allergic patients (p <0.05). Conclusion: Oxidative stress plays a role in the pathophysiology of allergic rhinitis, and thiol-disulfide hemostasis may be an indicator in allergic rhinitis. Key Words: Oxidative stress, Allergic rhinitis, Thiol, Disulfide, Cu, Zn.
dc.identifier.doi10.29271/jcpsp.2022.03.324
dc.identifier.endpage328en_US
dc.identifier.issue3en_US
dc.identifier.startpage324en_US
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/35148584/
dc.identifier.urihttps://hdl.handle.net/20.500.12868/2515
dc.identifier.volume32en_US
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofJ Coll Physicians Surg Pak .
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titleTrace Elements (Zn and Cu) and Oxidative Stress in Pediatric Patients with Persistent Allergic Rhinitis
dc.typeArticle

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