Low Serum Magnesium level can be a risk factor for Retinopathy in diabetic patients: A cross-sectional controlled study

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dc.contributor.authorBankır, Mehmet
dc.contributor.authorKeşkek, Nedime Şahinoğlu
dc.contributor.authorSaler, Tayyibe
dc.contributor.authorKeşkek, Şakir Özgür
dc.contributor.authorCevher, Selim
dc.date.accessioned2022-09-14T13:22:08Z
dc.date.available2022-09-14T13:22:08Z
dc.date.issued2021
dc.departmentALKÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractAim: Uncontrolled diabetes can lead to complications which are related to high blood sugar and insulin resistance (IR). A decrease in serum magnesium (Mg) levels can cause an increase in IR and a worsening of glycaemic control. In this study, we aimed to investigate the relationship between diabetic retinopathy (DR) and serum Mg levels. Methods: The study was designed as a cross-sectional study in the internal medicine department of a tertiary referral center (Adana Numune Training and Research Hospital) in Turkey. A total of 554 subjects, including 176 patients with DR patients, 209 patients without DR, and 169 healthy individuals were included in this study. Serum fasting glucose levels, insulin levels, homeostasis model assessment of insulin resistance (HOMA-IR), HbA1c percentages, and Mg levels were measured for all subjects. Results: Serum Mg level was lower in patients with DR (p<0.001). Furthermore; HOMA-IR, HbA1c and fasting glucose levels were higher in patients with DR (p<0.001, respectively). Incidence of DR was associated with serum Mg levels (odds ratio: 2.1, confidence interval: 95% 1.2-3.6, p=0.005). Conclusion: Low Mg level can lead to retinopathy by impairing glucose homeostasis. In patients with diabetes, Mg levels should be checked since Mg may be a supporting treatment.
dc.identifier.doi10.4274/haseki.galenos.2021.7188
dc.identifier.endpage344en_US
dc.identifier.issue4en_US
dc.identifier.startpage340en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12868/1623
dc.identifier.urihttps://hasekidergisi.com/articles/doi/haseki.galenos.2021.7188
dc.identifier.volume59en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.relation.ispartofHaseki Tıp Bülteni-Medical Bulletin of Haseki
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDiabetic retinopathy
dc.subjectHyperglycemia
dc.subjectInsulin resistance
dc.subjectMagnesium
dc.subjectType 2 diabetes mellitus
dc.titleLow Serum Magnesium level can be a risk factor for Retinopathy in diabetic patients: A cross-sectional controlled study
dc.typeArticle

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