Researching the Effects of Ellagic Acid on Depletion Exercise

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dc.contributor.authorKara, Ersan
dc.contributor.authorCoban, Funda Karabag
dc.contributor.authorAkil, Mustafa
dc.date.accessioned2026-01-24T12:26:52Z
dc.date.available2026-01-24T12:26:52Z
dc.date.issued2018
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractIntroduction: The purpose of this study was to investigate whether exhaustion exercise causes endothelial damage and to investigate the effect of ellagic acid on this potential damage. Methods and Materials: The study was carried out on 32 male and adult Spraque - Dawley rats at Experimental Animal Research and Research Center of Afyon Kocatepe University. The experimental animals were equally divided into four groups. Swimming exercises will be performed as acute exercises for once and experimental animals are made to swim in groups including two rats following the completion of the study and before the decapitation. At the end of procedures that last for four weeks, total oxidant (TOS), total antioxidant (TAS), nitric oxide (NO) and Asymmetric dimethyl Arginine (ADMA), TNF alpha, INF gamma and IL6 plasma and tissue levels was assayed from the blood samples to be taken from experimental animals with decapitation. Results: The data obtained as a result of the studies were evaluated by using SPSS 20.0 statistical program. Endothelial damage markers and cytokine levels were significantly (p<0,05) increased in swimming groups and ellagic acid significantly (p<0,05) decreased these parameters. Conclusion: Ellagic acid may have protective effect against damage that may occur during exhaustion exercise.
dc.description.sponsorshipUSAK BAP Project [2015MF/010]
dc.description.sponsorshipThe author wishes to thank Usak University, Scientific Research Coordination Division (USAK-BAP) for contribution to this research. This study was carried out within the USAK BAP Project No: 2015MF/010.
dc.identifier.doi10.9734/JPRI/2018/45923
dc.identifier.issn2456-9119
dc.identifier.issue2
dc.identifier.urihttps://doi.org/10.9734/JPRI/2018/45923
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4968
dc.identifier.volume25
dc.identifier.wosWOS:000462168100002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherSciencedomain Int
dc.relation.ispartofJournal of Pharmaceutical Research International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20260121
dc.subjectRat
dc.subjectellagic acid
dc.subjectendothelial damage
dc.titleResearching the Effects of Ellagic Acid on Depletion Exercise
dc.typeArticle

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