Evaluation of Association between PPARGC1A Gene Polymorphism and Competitive Performance of Elite Athletes

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dc.contributor.authorBulğay, Celal
dc.contributor.authorZorba, Erdal
dc.contributor.authorAkman, Onur
dc.contributor.authorBayraktarı, Işık
dc.contributor.authorKazan, Hasan Hüseyin
dc.contributor.authorErgun, Mehmet Ali
dc.contributor.authorUlucan, Korkut
dc.date.accessioned2023-06-15T14:16:29Z
dc.date.available2023-06-15T14:16:29Z
dc.date.issued2022
dc.departmentALKÜ, Fakülteler, Spor Bilimleri Fakültesi, Antrenörlük Eğitimi Bölümü
dc.description.abstractLimited number of researches exist on the relationship between PPARGC1A gene polymorphism (rs8192678) and affects the athletic performance. Thus, the present study aims to decipher any possible association of the rs8192678 polymorphism in the PPARGC1A gene with the competitive performances of Turkish elite track and field athletes. A total of 60 elite athletes (31 sprint/power and 29 endurance) and 20 control/sedentary with the ages of 18-35 voluntarily participated in the study. The International Association of Athletics Federations (IAAF) score scale was used to determine the performance levels of the personal best (PB) of the athletes. Whole exome sequencing (WES) was performed by the genomic DNA sample isolated from blood of the participants. The association between rs8192678 polymorphism and PB was examined by one-way analysis of covariance (ANCOVA) with the adjustment of sex and sport experience. According to the results, there were not any significant deviation between the wild-type (G/G), heterozygote (G/A) and homozygote (A/A) genotypes within and between the groups (p>0.05). Our results underlined that there were not any significances for association of rs8192678 polymorphism with PBs within the groups of the sprint/power and endurance athletes. However, it is recommended that similar studies be conducted with more participants to provide clearer information about the research.
dc.identifier.doi10.53434/gbesbd.1126033
dc.identifier.endpage332en_US
dc.identifier.issue4en_US
dc.identifier.startpage323en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1143752/evaluation-of-association-between-ppargc1a-gene-polymorphism-and-competitive-performance-of-elite-athletes
dc.identifier.urihttps://hdl.handle.net/20.500.12868/2247
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofGazi Beden Eğitimi ve Spor Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAthletics
dc.subjectSprint
dc.subjectPower
dc.subjectEndurance
dc.subjectPPARGC1A
dc.subjectPolymorphism
dc.subjectrs8192678
dc.subjectAtletizm
dc.subjectSürat
dc.subjectGüç
dc.subjectDayanıklılık
dc.subjectPPARGC1A
dc.titleEvaluation of Association between PPARGC1A Gene Polymorphism and Competitive Performance of Elite Athletes
dc.typeArticle

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