A CASE REPORT AND LITERATURE REVIEW OF PRIMARY ADRENOCORTICAL INSUFFICIENCY AS A COMPLICATION OF RHINO-ORBITAL-CEREBRAL MUCORMYCOSIS
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Tarih
2025
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Backgorund: Despite recent improvements in both diagnosis and treatment, rhino-orbital-cerebral mucormycosis (ROCM) is a life-threatening infection with a high mortality rate. Early diagnosis and treatment are crucial in terms of mortality and morbidity. Case: A 72-year-old female patient was hospitalised with the diagnosis of type 2 diabetes mellitus (DM), allergic asthma, and ROCM and discharged after iv liposomal amphotericin B treatment and surgical debridement. The patient, who was discharged after surgical and medical intervention, died due to the development of primary adrenal insufficiency. Conclusion: Lipid formulations of Amphotericin B and aggressive debridement form the basis of treatment. The most critical decision is whether the orbit should be exenterated or not. The development of side effects related to antifungal treatment has an impact on the mortality and morbidity of patients.
Açıklama
Anahtar Kelimeler
Primary adrenal insufficiency, Rhino-orbital-cerebral mucormycosis (ROCM), Amphotericin B treatment
Kaynak
ENTcase
WoS Q Değeri
Scopus Q Değeri
Cilt
11
Sayı
2
