Evaluation of anti-DFS70 antibodies and DFS pattern in ANA positive individuals and ANA Associated Rheumatic Diseases
| dc.contributor.author | Uğur, Sevcan | |
| dc.contributor.author | Kula Atik, Tuğba | |
| dc.date.accessioned | 2022-09-30T07:24:11Z | |
| dc.date.available | 2022-09-30T07:24:11Z | |
| dc.date.issued | 2021 | |
| dc.department | ALKÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | |
| dc.description.abstract | Aim: In this study we aimed to find the frequency of anti-DFS70 antibodies and DFS pattern in ANA positive individuals and ANA associated rheumatic diseases (AARDs). Methods: In this study, 337 subjects who were evaluated in a rheumatology clinic with prediagnosis of rheumatic diseases with positive ANA test and had concurrent anti-extractable nuclear antigen (anti-ENA) antibodies results were retrospectively analyzed. Clinical diagnosis of patients and demographic characteristics were obtained from the patients' medical records. Results: A total of 337 subjects (305 women, 32 men) were included in this study. The mean age was 49.8 ± 14.2 years. Of the 337 participants, 111 (32.9%) had an IIF-DFS pattern and 226 (67.1%) had a non-DFS pattern. Anti-DFS70 antibodies were positive in 20.1% of individuals. Sixty eight individuals had AARDs. An IIF-DFS pattern was observed in 22.1% and a non-DFS pattern was observed in 77.9% of individuals with AARDs (p <0.05). Anti-DFS70 antibodies were positive in 13.2% of patients with AARDs. The frequency of AARDs was significantly lower in individuals with anti-DFS70 antibodies compared to individuals with other anti-ENAs antibodies (p <0.05). Conclusion: Anti-DFS70 antibodies may be present in patients with AARDs but AARDs are less prevalent in patients who had anti-DFS70 antibodies, compared with patients who had other anti-ENAs | |
| dc.identifier.doi | 10.30565/medalanya.952813 | |
| dc.identifier.endpage | 238 | en_US |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.startpage | 234 | en_US |
| dc.identifier.uri | https://dergipark.org.tr/tr/download/article-file/1825698 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12868/1726 | |
| dc.identifier.volume | 5 | en_US |
| dc.language.iso | en | |
| dc.relation.ispartof | Acta Medica Alanya | |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Antinuclear antibodies (ANA) | |
| dc.subject | Anti DFS70 antibody | |
| dc.subject | DFS patter | |
| dc.title | Evaluation of anti-DFS70 antibodies and DFS pattern in ANA positive individuals and ANA Associated Rheumatic Diseases | |
| dc.type | Article |
