Pelvic parameters as prognostic factors of radiographic progression in classical Ankylosing Spondylitis: A prospective follow-up data

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dc.contributor.authorAbacar, Kerem Yi?it
dc.contributor.authorÇolakoğlu-Özkaya, Şeyma
dc.contributor.authorBiyikli, Erhan
dc.contributor.authorBuğdaycı, Onur
dc.contributor.authorKurşun, Meltem
dc.contributor.authorDenizli, Ayberk
dc.contributor.authorKocak, Beril
dc.date.accessioned2026-01-24T12:20:43Z
dc.date.available2026-01-24T12:20:43Z
dc.date.issued2024
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractRadiographic progression in Ankylosing spondylitis (AS) is driven by mechanical strain. A well-balanced spine provides a favorable weight distribution across the entheses. Pelvic parameters are useful in assessing the shape of the spine. The present study aimed to prospectively investigate the predictive value of pelvic parameters for radiographic progression in AS. This non-interventional, observational, and prospective study enrolled AS patients fulfilling the modified New York criteria (mNY) currently under follow-up in the MARS (MARmara Spondyloarthritis) outpatient clinics. The primary objective was to investigate the relationship between the baseline pelvic parameters and radiographic progression in the spine. Two trained radiologists (EB, OB) independently assessed the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS). An orthopedic surgeon (AHA) and a radiologist (EB) derived the pelvic parameters. Patients with no bridging or bamboo spine were included in the final analysis. Risk assessment for radiographic progression, defined as a two-unit increase in mSASSS or developing a new syndesmophyte every two years, was done using uni- and multivariate logistic regression analyses. Radiographs of 69 AS patients were analyzed. The median (IQR 25–75) prospective follow-up was 47.7 (34.6–52.8) months. Only 33.3% (23/69) had radiographic progression. The pelvic tilt (PT) was lower in patients with radiographic progression (p = 0.037) and each degree of decrease in PT provided a 9% increase in risk for radiographic progression. Male patients were 7.5 times more likely to progress. Pelvic parameters provide a prognostic insight into the radiographic progression in AS. Our observations may aid in selecting patient-specific interventions in addition to anti-inflammatory treatments. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.
dc.description.sponsorship(219S794)
dc.identifier.doi10.1007/s00296-024-05646-w
dc.identifier.endpage2430
dc.identifier.issn0172-8172
dc.identifier.issue11
dc.identifier.scopus2-s2.0-85197762016
dc.identifier.scopusqualityQ1
dc.identifier.startpage2421
dc.identifier.urihttps://doi.org/10.1007/s00296-024-05646-w
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4531
dc.identifier.volume44
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.relation.ispartofRheumatology International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20260121
dc.subjectadult
dc.subjectankylosing spondylitis
dc.subjectAnkylosing Spondylitis Disease Activity Score
dc.subjectArticle
dc.subjectbiological therapy
dc.subjectbody mass
dc.subjectcervical spine
dc.subjectcross-sectional study
dc.subjectdemographics
dc.subjectfemale
dc.subjectfollow up
dc.subjecthealth care quality
dc.subjecthuman
dc.subjectjoint surgery
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmultivariate logistic regression analysis
dc.subjectobservational study
dc.subjectorthopedic surgeon
dc.subjectoutpatient department
dc.subjectpelvic angle
dc.subjectpelvic incidence
dc.subjectpelvic tilt
dc.subjectprognosis
dc.subjectprospective study
dc.subjectradiologist
dc.subjectsacral slope
dc.titlePelvic parameters as prognostic factors of radiographic progression in classical Ankylosing Spondylitis: A prospective follow-up data
dc.typeArticle

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