Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research

dc.contributor.authorBulğay, Celal
dc.contributor.authorBayraktar, Işık
dc.contributor.authorOdemıs, Merıc
dc.contributor.authorYildirim, Damla Selin
dc.contributor.authorErgun, Mehmet Ali
dc.contributor.authorCerıt, Mesut
dc.contributor.authorUlucan, Korkut
dc.date.accessioned2026-01-24T12:01:34Z
dc.date.available2026-01-24T12:01:34Z
dc.date.issued2023
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractObjective: The present study aims to examine investigation the ?-actinin-3 (ACTN3) gene polymorphism (rs1815739) and functional movement screen (FMS) values in young runners competing at the national level. Material and Methods: Forty-five young runners (29 male 64.4%, 16 female 35.6%) competing at the national level in different clubs affiliated to the Turkish Athletic Federation and training regularly at least 5 days a week voluntarily participated in the study. The DNA isolation of oral swab samples was carried out using the spin column (MN Macherey-Nagel, Germany) method. The genotyping pro- cess was performed using the real-time polymerase chain reaction method. Results: The FMS test battery was used to determine the functional capacity. According to the findings obtained, it was determined that in the FMS evaluation of the female runners, the runners with the CC genotype had a significantly higher mean score compared to the runners with the CT genotype (p<0.033) while in the male runners, the runners with the CT genotype had a significantly higher mean score compared to the runners with the TT genotype (p<0.031). However, in the FMS evaluation of the overall runners, no significant difference was found (p>0.205). Conclusion: It is thought that the FMS test battery and the ACTN3 gene polymorphism, which is among the important variables responsible for non-impact injuries, can be effective in the level of muscle damage, the type of muscle injury, the prediction of injuries and reducing the risk factors that may cause injuries.
dc.identifier.doi10.5336/sportsci.2022-94239
dc.identifier.endpage229
dc.identifier.issn1308-0938
dc.identifier.issn2146-8885
dc.identifier.issue2
dc.identifier.startpage223
dc.identifier.trdizinid1188524
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1188524
dc.identifier.urihttps://doi.org/10.5336/sportsci.2022-94239
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4432
dc.identifier.volume15
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürkiye Klinikleri Spor Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR-Dizin_20260121
dc.subjectGenetik ve Kalıtım,Spor Bilimleri
dc.titleInvestigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research
dc.typeArticle

Dosyalar