Efficacy of blood parameters as indicators of the need for overdue urgent cholecystectomy in elderly patients with acute cholecystitis

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dc.contributor.authorKubat, Mehmet
dc.contributor.authorŞengül, Serkan
dc.contributor.authorŞahin, Serdar
dc.date.accessioned2026-01-24T12:01:34Z
dc.date.available2026-01-24T12:01:34Z
dc.date.issued2023
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description.abstractBACKGROUND: Although early cholecystectomy is recommended for patients with acute cholecystitis, conservative treatment followed by delayed cholecystectomy (DC) is a highly preferred modality, especially in older adult patients. However, some severe cases require overdue urgent cholecystectomy (OC). This study aimed to evaluate the ability of laboratory findings and Tokyo severity classification (TokyoSC) to differentiate those with the need for OC among elderly patients. METHODS: Laboratory/radiological/clinical findings of geriatric patients with acute cholecystitis on admission and TokyoSC were retrospectively analyzed. The DC and OC groups were compared. RESULTS: The mean age of the 164 patients was 72.3±6.4 years. White blood cell, neutrophil (NEU), immature granulocyte (IG), C-reactive protein, neutrophil-to-lymphocyte ratio (NLR), and TokyoSC parameters were all significant at P<0.001 in differentiation. NLR had a specificity of 98%, and TokyoSC had a sensitivity of 98%. CONCLUSION: NLR, NEU, IG, and TokyoSC were effective in differentiating patients who needed OC while planning conservative treatment + DC for older adult patients who were followed up due to acute cholecystitis. If the NLR is >9.9 and TokyoSC is moderate/ high, early cholecystectomy should be preferred instead of conservative treatment + DC in aged patients.
dc.identifier.doi10.14744/tjtes.2023.75670
dc.identifier.endpage1254
dc.identifier.issn1306-696X
dc.identifier.issn1307-7945
dc.identifier.issue11
dc.identifier.startpage1248
dc.identifier.trdizinid1264629
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1264629
dc.identifier.urihttps://doi.org/10.14744/tjtes.2023.75670
dc.identifier.urihttps://hdl.handle.net/20.500.12868/4440
dc.identifier.volume29
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofUlusal Travma ve Acil Cerrahi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR-Dizin_20260121
dc.subjectNeutrophil-to-lymphocyte ratio
dc.subjectaged
dc.subjectcholecystectomy
dc.subjectc-reactive protein
dc.subjectAcute cholecystitis
dc.subjectseverity grading.
dc.titleEfficacy of blood parameters as indicators of the need for overdue urgent cholecystectomy in elderly patients with acute cholecystitis
dc.typeArticle

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