An experimental study to investigate the impact of Aspirin and Vitamin C therapy on fructose induced hepatic and pancreatic damage

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dc.contributor.authorYeşilot, Şükriye
dc.contributor.authorÖzer, Mehmet Kaya
dc.contributor.authorGültekin, Fatih
dc.contributor.authorÖncü, Meral
dc.contributor.authorCandan, İbrahim Aydın
dc.contributor.authorDağdeviren, Birsen Harun
dc.contributor.authorÇiçek, Ekrem
dc.date.accessioned2026-01-24T11:55:18Z
dc.date.available2026-01-24T11:55:18Z
dc.date.issued2022
dc.departmentAlanya Alaaddin Keykubat Üniversitesi
dc.description3102-D–12
dc.description.abstractIt is assumed that excessive fructose consumption is associated with the risk of developing various diseases, especially metabolic disease. The aims of this study were two fold: 1) Does liver and pancreatic damage occur due to excessive fructose consumption 2) If damage occurs, can we reduce this damage by using (ASA) and Vit. C. The rats were divided randomly into five groups of eight as follows: Group1-control; Group2-corn syrup (Fructose: F; 30% F solution); Group3-F and ASA (F+10 mg/kg/day, ASA, oral); Group4-F and Vit. C (F+200 mg/kg/day, Vit. C, oral); Group5-F, ASA and Vit C (F+A+C -same dose administration, respectively). The rats were sacrificed 24 h after the last application at the end of the 6th week, and their blood serum, liver and pancreas tissues were taken and evaluated histologically and biochemically. It was found that serum cholesterol and AST levels were significantly lower in the F+C and F+A+C groups, and ALT and TG levels were significantly lower in the F+A+C group compared to the F group (p
dc.description.sponsorshipSüleyman Demirel Üniversitesi Bilimsel Araştırma Projeleri Yönetim Birimi t
dc.identifier.doi10.56150/tjhsl.1143635
dc.identifier.endpage131
dc.identifier.issn2687-2730
dc.identifier.issn2687-2730
dc.identifier.issue2
dc.identifier.startpage121
dc.identifier.urihttps://doi.org/10.56150/tjhsl.1143635
dc.identifier.urihttps://hdl.handle.net/20.500.12868/2819
dc.identifier.volume5
dc.language.isoen
dc.publisherMümin POLAT
dc.relation.ispartofTurkish Journal of Health Science and Life
dc.relation.ispartofTurkish Journal of Health Science and Life
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20260121
dc.subjectHealth Care Administration
dc.subjectSağlık Kurumları Yönetimi
dc.titleAn experimental study to investigate the impact of Aspirin and Vitamin C therapy on fructose induced hepatic and pancreatic damage
dc.typeArticle

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