The association between contrast associated acute kidney injury and direct bilirubin levels
dc.contributor.author | Kaya, Yasemin | |
dc.contributor.author | Kaya, Ahmet | |
dc.contributor.author | Karataş, Ahmet | |
dc.contributor.author | Bektaş, Osman | |
dc.contributor.author | Yenerçağ, Mustafa | |
dc.contributor.author | Akkaya, Fatih | |
dc.date.accessioned | 2022-09-30T07:31:34Z | |
dc.date.available | 2022-09-30T07:31:34Z | |
dc.date.issued | 2021 | |
dc.department | ALKÜ | |
dc.description.abstract | Aim: In this study we aimed to association between bilirubin levels, which is known to have anti-oxidative, anti-inflammatory and anti-thrombotic effects, and contrast associated acute kidney injury (CA-AKI) in patients with acute coronary syndrome (ACS). Methods: Between 2017-2020, consecutive patients over 18 years of age who applied percutaneous angioplasty with the ACS diagnosis and met the exclusion and inclusion criteria (n:514) were retrospectively screened. Age, gender, chronic diseases and complete blood count parameters of the cases were recorded. Biochemical parameters, before applying contrast and 48 hours after applying contrast, were recorded. A 25% increase in creatinine level measured 48 hours after contrast application compared to basal creatinine was defined as CA-AKI. Results: CA-AKI rate was higher in females(p=0.011). In the CA-AKI positive patient group, the mean age was found significantly higher (p=0.04), hemoglobin (p=0.007), direct bilirubin (p=0.008) levels were found significantly lower. Direct bilirubin was found to be a predictor as a result of our statistical analysis to identify independent predictors of CA-AKI (Beta:0.051 OR 95% CI:0.007-0.392, p=0.004). It was found that the direct bilirubin value of 0.065 predicted CA-AKI with 90% sensitivity and 91% specificity. Conclusions: It was observed that the direct bilirubin values were significantly lower in the CA-AKI positive patient group, and the direct bilirubin value of 0.065 predicted CA-AKI with 90% sensitivity and 91% specificity. | |
dc.identifier.doi | 10.30565/medalanya.887847 | |
dc.identifier.endpage | 249 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 244 | en_US |
dc.identifier.uri | https://dergipark.org.tr/tr/download/article-file/1605899 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12868/1728 | |
dc.identifier.volume | 5 | en_US |
dc.language.iso | en | |
dc.relation.ispartof | Acta Medica Alanya | |
dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Başka Kurum Yazarı | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Contrast associated acute kidney injury | |
dc.subject | Direct bilirubin | |
dc.subject | Bilirubins | |
dc.title | The association between contrast associated acute kidney injury and direct bilirubin levels | |
dc.type | Article |