Yazar "Uslu, Mustafa Ozay" seçeneğine göre listele

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    Effects of Peri-implant Mucosal Characteristics on Clinical Peri-implant Parameters: A Retrospective Study
    (Galenos Publ House, 2023) Bozkurt, Esra; Uslu, Mustafa Ozay
    Objective: This study aimed to examine the effects of peri-implant keratinized mucosa (KM) width and thickness on peri-implant soft tissue health in functionally loaded implants and evaluate the factors affecting peri-implant health. Materials and Methods: A total of 645 implants from 169 patients were evaluated in this study. The duration of the implant followup ranged from 12 months to 46 months. Clinical measurements such as plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL), KM width, mucosal phenotype (MP), and buccal mucosal recession (MR) of peri-implant sites were performed. Peri-implant mucosa was classified as healthy, peri-implant mucositis, and peri-implantitis. Results: It was determined that the thickness and width of the KM around the implant did not affect the peri-implant soft tissue health and PI, GI, and BOP scores. PD was found to be significantly lower in peri-implant regions with KM width <2 mm and thin MP. CAL was found to be significantly higher in peri-implant regions with KM width <2 mm and thin MP. Significantly less buccal MR was detected in peri-implant regions with KM width & GE;2 mm and thick MP. The peri-implant regions treated with the overdenture were significantly less healthy. Conclusions: It was determined that the CM width and thickness around the implant did not have a significant effect on soft tissue health in patients who could achieve plaque control. It is important to provide sufficient KM width and thickness in the peri-implant soft tissue, especially in esthetic areas.
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    Öğe
    Preventive effects of systemic Pistacia eurycarpa Yalt. administration on alveolar bone loss and oxidative stress in rats with experimental periodontitis
    (Univ Sao Paulo Fac Odontologia Bauru, 2024) Atalay, Mustafa; Uslu, Mustafa Ozay; Icen, Mehmet Sina; Uremis, Nuray; Turkoz, Yusuf
    Objective: This study aimed to investigate the effects of systemic administration of P. eurycarpa Yalt. plant extract on alveolar bone loss and oxidative stress biomarkers in gingival tissue in a rat model of experimental periodontitis. Methodology: 32 male Wistar albino rats, weighing 200-250 g, were divided into four groups (n=8): Healthy control (HC), Experimental periodontitis control (EPC), Experimental periodontitis 400 mg/kg (EP400), Experimental periodontitis 800 mg/kg (EP800). Experimental periodontitis was induced using the ligating method. Distilled water was administered to the HC and EPC groups and the plant extract was administered to the EP400 and EP800 groups by oral gavage at doses of 400 mg/kg and 800 mg/kg, respectively. The rats were sacrificed on the 15th day. The values of glutathione peroxidase GSH-Px, malondialdehyde (MDA), superoxide dismustase (SOD), interleukin-113 (IL-113), interleukin-10 (IL-10), total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI) in the gingival tissues were analyzed by ELISA tests. Alveolar bone loss was assessed using micro-CT images of the maxilla. Results: Although the IL-113, TOS, OSI results of the healthy control group were lower than those of the other groups, the TAS values were higher (p<0.05). No significant difference was found in the biochemical parameters among the EPC, EP400, and EP800 groups (p>0.05). Alveolar bone loss was significantly reduced in the extract groups compared to the EPC group (p<0.001). Conclusion: Within the limitations of this study, it was observed that the systemic P. eurycarpa extract application reduced alveolar bone loss in a rat model of experimental periodontitis. Further studies are needed to elucidate the beneficial effects