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    Biomechanical and Histologic Evaluation of Osseointegration of Titanium Dental Implants Modified by Various Combinations of Sandblasting, Acid-Etching, Hydroxyapatite, and Hyaluronic Acid Coating Techniques
    (Quintessence Publishing Co Inc, 2023) Yurttutan, Emre; Dereci, Omur; Karagoz, Mine Alkaya
    Purpose: To compare the osseointegration process of the titanium dental implants with five different surface characteristics-sandblasted, sandblasted and acid-etched, hyaluronic acid-coated (HYA), hydroxyapatite-coated (HA), and machined-in an experimental sheep model at 1- and 3-month examinations. Materials and Methods: One hundred sixty dental implants were placed in the left and right tibias of 16 sheep. Five experimental groups were designed. Eight animals (80 implants) were used for biomechanical tests of reverse torque analysis and resonance frequency analysis (RFA). Eight of them (80 implants) were used for the evaluation of bone-to-implant contact (BIC) percentage in histomorphometric analysis. Forty of 80 implants (8 implants for each group) were used at 1-month examinations, and the remaining 40 (8 implants for each group) implants were used at 3-month examinations in the biomechanical test group and histomorphometric examination group, separately. Results: Intergroup analysis at the 3-month follow-up showed that the increase in the implant stability quotient (ISQ) value was statistically significant for only the HYA group (P < .05). According to ISQ values at 1 and 3 months, group HYA showed statistically higher values at the 1 and 3- month examinations (P < .05). Groups HYA and HA had statistically higher reverse torque values than other groups at the 1-month examination (P < .05). At the 3-month evaluation, the HYA group showed significantly higher reverse torque values compared to other groups (P < .05). The BIC values of the sandblasted and acid-etched, HYA, and HA groups were significantly higher than the sandblasted and machined groups at the 1- and 3- month examinations (P < .05). The BIC value for the HA group showed decreased value at the 3-month examination compared to the 1-month examination (P <.05). Conclusion: The RFA, reverse torque, and histomorphometric analysis at 1- and 3-month examinations show that dental implants coated with HYA may have increased potential for osseointegration compared to dental implants with sandblasted, sandblasted and acid-etched, machined, and HA-coated surfaces.
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    The effect of music and white noise on patients' anxiety and pain during surgery for impacted mandibular third molar: a single-blind randomized controlled trial
    (Bmc, 2025) Karagoz, Mine Alkaya; Altundogan, Serpil
    Background Anxiety during oral surgery adversely affects patients' compliance with treatment and patient-doctor cooperation. Therefore, various treatment protocols have been developed to reduce anxiety. This study aimed to evaluate the effects of music and white noise on patients' anxiety and pain during surgery for impacted third molars. Methods According to the Consolidated Standards of Reporting Trials statement, this single-blind, randomized, controlled trial with parallel groups involved 66 patients who met the eligibility criteria and were randomly assigned to one of three groups. Group 1 listened to preselected songs played against a pre-prepared standard white noise through noise-isolating headphones that block ambient noise during the procedure. Group 2 listened only to music through noise-isolating headphones during the procedure. Group 3 listened to natural ambient noise during the procedure. All surgical procedures were performed in a standard operating room. All patients completed the State-Trait Anxiety Inventory-State (STAI-S) form and indicated their anxiety on a Visual Analog Scale (VAS) preoperatively and postoperatively. They also indicated the pressure/pain level they felt during the procedure on a VAS. The primary predictor variable was the music and white noise intervention. The primary outcome variables were the STAI-S and VAS scores. Sex was included as a covariate. Results Anxiety VAS scores were significantly lower postoperatively than preoperatively in Groups 1 (p < 0.001), 2 (p < 0.001), and 3 (p = 0.002). Similarly, STAI-S scores were significantly lower postoperatively than preoperatively in Groups 1 (p < 0.001), 2 (p < 0.001), and 3 (p = 0.012). The change in STAI-S scores (p = 0.053) did not differ significantly between groups. Conclusion Although not statistically significant, listening to music alone or with white noise reduced the anxiety experienced by patients during the procedure and increased their comfort. As a simple, inexpensive, and non-invasive method, listening to self-selected music in the preoperative and perioperative periods could benefit patients.